Research
Latest published research we're tracking.
The newest skincare and haircare papers from PubMed, linked to the ingredients we decode. Summaries are the authors' own abstracts — we excerpt, attribute, and link out to the source.
124 papers under Cosmetic safety
Heavy Metal Toxicity in Clinical and Environmental Health: Sources, Mechanisms, Diagnostics, and Evidence-Based Management of Mercury, Lead, Cadmium, and Arsenic.
International journal of molecular sciences · 2026
Heavy metals including mercury (Hg), lead (Pb), cadmium (Cd), and arsenic (As) remain significant global toxins due to their environmental persistence, widespread anthropogenic release, and serious biological effects. This review consolidates current understanding of their natural and industrial sources, environmental cycling, human exposure routes, and population-level vulnerabilities. It covers… Read on PubMed →
Human Milk as a Biomonitor of Toxic Metal Exposure: Sources, Transfer Mechanisms, and Implications for Infant Health-A Review.
Nutrients · 2026
Human milk (HM) is recognized as the optimal source of nutrition for infants, providing essential nutrients, bioactive compounds, and immunological protection crucial for proper growth and development. However, due to increasing environmental pollution, HM may also serve as a vector for exposure to toxic substances, including heavy metals. These contaminants originate from both current… Read on PubMed →
Concentrations and Probabilistic Health Risks of Seven Metals in Face and Eye Cosmetics Across Seven Asian Countries.
Toxics · 2026
Despite global restrictions like the Minamata Convention, heavy metal contamination in cosmetics remains a critical public health concern, with limited cross-country comparative data on heavy metal concentrations in cosmetics across Asian markets. We measured Hg, Pb, As, Cd, Sb, Cr, and Ni contents in 189 cosmetic products purchased in 2022 in Bangladesh, India, Indonesia, Korea, Malaysia, the… Read on PubMed →
Exploration of Natural Adsorbents for Applications in Pollution-Reducing Cosmetic Formulations.
Gels (Basel, Switzerland) · 2026
Human skin and hair act as multifunctional barriers but are highly sensitive to environmental pollutants originating from air, water, and cosmetic products. Epidemiological studies report that exposure to particulate matter (PM<sub>2.5</sub>-PM<sub>10</sub>), nitrogen oxides (NO<sub>x</sub>), and volatile organic compounds increases the risk of skin and hair disorders. For instance, women in… Read on PubMed →
The way forward for assessing the human health safety of cosmetics in the EU: Proceedings of Workshop 2.
Archives of toxicology · 2026
Under the European Cosmetic Regulation, safety assessments of cosmetics and their ingredients must be conducted without the use of animals. This regulatory requirement poses a number of challenges, as validated alternative methods are only available for some of the toxicological endpoints that are typically considered in standard human health risk assessments. Despite significant progress since… Read on PubMed →
Periocular necrotizing sweet syndrome - a case series and review of literature.
Orbit (Amsterdam, Netherlands) · 2026
Sweet syndrome (SS), or acute neutrophilic dermatosis, is a dermatologic condition characterized by fever and neutrophilia with tender papular or plaque-like eruptions; diagnosis is confirmed histologically and the disease typically responds to systemic corticosteroids. Ocular associations include conjunctivitis, peripheral ulcerative keratitis, scleritis, uveitis, glaucoma, and retinal… Read on PubMed →
Consumer preferences for the development of new emulsion products based on vegetable and animal fats.
PloS one · 2026
The purpose of this paper was to determine consumer preferences for the acceptance of a new emulsion product containing interesterified fat based on mutton tallow and hemp oil. The survey concerned consumers' reference to the new emulsion products as pharmaceutical, food, and cosmetic products. On the basis of the survey, it was concluded that the hypothetical emulsion products would gain consumer… Read on PubMed →
GKB7I-53: A novel anti-metastatic agent for colorectal cancer.
Toxicology and applied pharmacology · 2026
Metastasis driven by epithelial-mesenchymal transition (EMT) remains a critical challenge in colorectal cancer treatment. This study investigated GKB7I-53, a saponin compound isolated through feature-based molecular networking, as a potential therapeutic agent targeting EMT pathways. GKB7I-53 demonstrated minimal cytotoxicity (>90% cell viability at 50 μM) while effectively inhibiting metastatic… Read on PubMed →
Bilateral superior labial artery embolization for arteriovenous malformation.
Minerva dental and oral science · 2026
Lip arteriovenous malformations (AVMs) are typically present at birth and can lead to progressive tissue destruction and functional and cosmetic issues. Their management is challenging due to the lack of standardized protocols and may involve both surgical and non-surgical approaches. The authors present a case of upper lip AVM with feeders bilaterally from both facial arteries and their superior… Read on PubMed →
Unraveling the molecular mechanisms of aluminium chloride-induced Alzheimer's disease.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
The most prevalent neurodegenerative illness is Alzheimer's disease (AD). Aluminium chloride (AlCl3) is a heavy metals that produces several neurodegenerative diseases, commonly AD. AlCl3 easily goes through the blood-brain barrier and reaches to brain. In this study, we reviewed literature, highlighting the various molecular mechanisms targeting AlCl3-induced neurodegenerative disorders like AD… Read on PubMed →
Injectable Nuances for the Male Face.
Facial plastic surgery : FPS · 2026
Minimally invasive cosmetic procedures consistently lead the aesthetic landscape year after year. Men are increasingly requesting aesthetic interventions with a focus on maintaining a youthful, powerful, and natural look. There are significant anatomical, physiological, and behavioral differences in the aging male face that warrant specific treatment considerations.Literature review of male… Read on PubMed →
Lost in NAMs-lation: A review of animal-free science definitions.
ALTEX · 2026
The use of terminology related to animal-free science has grown rapidly over the past two decades; however, definitions and interpretations of key terms remain inconsistent across global regulatory, scientific, and policy contexts. The term “new approach methodology(ies)” (NAM(s)) exemplifies this issue: though rarely used prior to 2019, its uptake in scientific literature has increased… Read on PubMed →
Ethno-cultural risk of ante-natal lead exposure among South Asian women in the UK.
Social science & medicine (1982) · 2026
BACKGROUND: Maternal lead exposure, shaped by environmental and cultural factors, can transfer to the foetus. Culturally embedded practices among South Asian women, including dietary habits and traditional cosmetics, may increase exposure compared with Caucasian women. This study measured ante-natal blood lead levels in South Asian mothers in Leeds, UK, and examined associated environmental… Read on PubMed →
Determination of cannabinoids in commercial hemp seeds and hemp seed oil products in Türkiye by LC-MS/MS.
Forensic science international · 2026
Hemp seeds and hemp seed oil are consumed both as cosmetics and as dietary supplements. Many countries have implemented legal regulations establishing thresholds for cannabinoids, particularly Δ9-tetrahydrocannabinol (Δ9-THC), in hemp seeds and hemp seed oil. This study presents the development and validation of a LC-MS/MS method for the quantitative determination of Δ9-tetrahydrocannabinol… Read on PubMed →
Research progress on extraction, processing technology and pharmacological action of Polygonatum polysaccharides: A review.
International journal of biological macromolecules · 2026
The genus Polygonatum is distributed throughout the temperate northern hemisphere and has been widely used worldwide as a food and medicinal ingredient. Polysaccharides are an important active component in Polygonatum. More and more studies have shown that Polygonatum has a wide range of biological functions. In this paper, we reviewed the latest progress of extraction, separation, structure… Read on PubMed →
Predicting Fiber Specificity on Gut Microbiome Modulation.
Annual review of food science and technology · 2026
Dietary fibers are crucial in shaping gut microbial composition and functionality. Physical complexity and chemical interactions between fibers and the gut environment lead to diverse and specialized responses that involve entire food webs of gut bacteria; however, there is comparatively less emphasis on understanding ecological dynamics to predict these outcomes. These responses may potentially… Read on PubMed →
Dangerous Anatomical Zones in Terms of Vascular Structures for Filler Injections to the Temporal Region: A Morphometric CT Angiography Study.
Aesthetic plastic surgery · 2026
BACKGROUND: Filler procedures in the temporal region are frequently preferred in aesthetic practice; however, the complex vascular anatomy of this area poses significant risks. Misplaced injections into the superficial temporal artery (STA) or the zygomatico-orbital artery (ZOA) can cause blindness, while those into the middle temporal vein (MTV) may lead to pulmonary embolism. Therefore, a… Read on PubMed →
Talc fits the framework of poorly soluble low-toxicity particles - implications for hazard classification.
Regulatory toxicology and pharmacology : RTP · 2026
An extensive toxicology database demonstrates talc exhibits the defining characteristics of poorly soluble, low-toxicity particles (PSLTs), including slow dissolution in biological fluids; macrophage-mediated clearance as the key determinant of lung residence time; significant inflammatory and proliferative responses only at lung burdens that overload normal particle clearance capacity; and, lung… Read on PubMed →
Detection of phthalate compounds in wet wipes using LC-MS/MS: risk assessment and LC-QTOF/MS findings.
Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering · 2026
Phthalates, widely used as plasticizers, pose significant health risks due to their endocrine-disrupting properties. This study aimed to determine the concentrations of 11 phthalate derivatives, including diethyl phthalate (DEP), bis(2-ethylhexyl) phthalate (DEHP), di-n-octyl phthalate, and dimethyl phthalate, in wet wipe samples using LC-MS/MS. A total of 15 wet wipe samples were randomly… Read on PubMed →
Zinc oxide nanoparticles from drug delivery to immunomodulation: progress and challenges.
Expert opinion on drug delivery · 2026
INTRODUCTION: Over the last decades, zinc oxide nanoparticles (ZnO NPs) have emerged as promising nanoplatforms for various biomedical applications. This critical perspective summarizes the main uses of ZnO NPs in cancer therapy, focusing on their roles in advanced drug delivery, stimuli-responsive systems, and immunomodulatory treatments targeting tumor tissues. AREAS COVERED: Due to their… Read on PubMed →