Latest published research we're tracking.

Poly(2-oxazoline) and poly(2-oxazine)-based nanomedicines: Advancements, opportunities and challenges.

Journal of controlled release : official journal of the Controlled Release Society · 2026

For 50 years poly(ethylene glycol) (PEG) has been regarded as the gold standard of biocompatible, hydrophilic, and stealthy nanomedicine excipients. PEG has demonstrated improved pharmacokinetic profile, improved physical stability, and reduced toxicity for a variety of therapeutic molecules. PEG and PEG derivatives are ubiquitous, present in nearly all lipid nanoparticle vaccines, oncology… Read on PubMed →

Hemp seed protein: a promising meat protein substitute with high nutritional value, high safety, and high meat like aroma characteristics.

Food chemistry · 2026

Despite advances in alternative proteins, it remains unclear whether novel plant proteins can achieve high nutritional digestibility, safety, and meat-like flavor. Therefore, this study evaluates hemp seed protein as a meat substitute through comparison with other alternative proteins and beef. Nutritional analyses (amino/fatty acid composition, in vivo/in vitro digestibility) showed that Hemp… Read on PubMed →

A Case Report and Literature Review: Chlorhexidine-induced anaphylaxis in a hemodialysis patient.

Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia · 2026

Chlorhexidine is a widely used antiseptic in healthcare settings, particularly for catheter site preparation in hemodialysis patients. While generally considered safe, chlorhexidine can rarely cause severe IgE-mediated anaphylactic reactions. Here we report the case of a 47-year-old man on maintenance hemodialysis who experienced two episodes of severe allergic reactions during dialysis sessions… Read on PubMed →

Epithelial Barrier Dysfunction in Atopic Dermatitis, Allergic Contact Dermatitis, and Chronic Spontaneous Urticaria and its Therapeutic Implications.

Current allergy and asthma reports · 2026

PURPOSE OF REVIEW: Allergic skin diseases arise from complex interactions between epithelial barrier dysfunction and immune dysregulation. This review examines how structural and functional defects in the epidermal barrier predispose to conditions such as atopic dermatitis, allergic contact dermatitis, and chronic spontaneous urticaria, and explores how mechanistic insights into these… Read on PubMed →

Peptide-enriched hydrogel formulation for sensitive and damaged skin: from design to application testing.

Scientific reports · 2026

Various factors such as infections, wounds, and comorbidities can disrupt the skin's physiological function. Moreover, skin lesions can result from radiation therapy. We aimed to create a new cosmetic formulation with pro-regenerative properties that is specifically designed for patients with sustained skin damage, such as those who have undergone radiation therapy. In the first stage, NE1 and IM2… Read on PubMed →

Smarter Skin Delivery: Nanosomes and Advanced Nanocarriers in Cutting-Edge Cosmetics.

Molecules (Basel, Switzerland) · 2026

Nanosomes-lipid vesicles at the nanoscale-enable the encapsulation of both hydrophilic and lipophilic actives and are increasingly used as skin delivery systems in cosmetic products. Alongside nanoemulsions, polymer nanocapsules, and inorganic nanoparticles (e.g., TiO2, ZnO, Ag), they can enhance solubility, stability, residence time, and local bioavailability while enabling controlled release… Read on PubMed →

A Parade of Persistent and Emerging Contact Allergens - A Clinical Update.

Current allergy and asthma reports · 2026

PURPOSE OF REVIEW: Clinical management of allergic contact dermatitis (ACD) is increasingly challenging due to the growing number of allergens, complex exposure patterns, and evolving regulatory frameworks. This review aims to provide clinicians with an updated overview of well-known as well as new and emerging allergens relevant to the diagnosis and management of ACD. RECENT FINDINGS: Recent… Read on PubMed →

An Inorganic Stimulator of Interferon Genes Sensitizer for the Metalloimmunotherapy of Intracellular Bacterial Infections.

ACS nano · 2026

Bone infections associated with the formation of intracellular bacterial niches in macrophages and bone cells play an important role in the long-lasting nature of chronic infections. One major mechanism of intracellular bacterial persistence lies in the low antibiotic permeability and subverted immune responses. It is now increasingly apparent that metal elements such as Mn, Zn, and Se exploit the… Read on PubMed →

Pseudo-Psoriatic Nail Dystrophy Associated With Cosmetic Nail Products.

Journal of drugs in dermatology : JDD · 2026

Pseudo-psoriatic nail dystrophy, a form of allergic contact dermatitis (ACD) secondary to nail product use, often mimics nail changes associated with psoriasis, leading to diagnostic delays. This review focuses on identifying dystrophic nail changes, particularly those resembling pseudo-psoriatic alterations, caused by cosmetic nail products and offers diagnostic and management strategies. Among… Read on PubMed →

Magnolol suppresses TKI-resistant EGFR-mutant lung cancer by inhibiting EGFR and AXL-cMyc.

European journal of pharmacology · 2026

Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), particularly osimertinib, remains a major therapeutic challenge in EGFR-mutant lung cancer. In this study, we evaluated the pharmacological activity of magnolol, a natural biphenolic compound, in EGFR-mutant lung cancer models, including osimertinib-resistant cells harboring tertiary mutations such as… Read on PubMed →

Alternative in vitro and in silico models to reduce animal use: a crucial technological advance in dermatological sciences.

Expert reviews in molecular medicine · 2026

INTRODUCTION: Alternative models are tools to replace and reduce the number of animals used in biomedical sciences, for either research or tests of industrial products. Several new alternative models have been developed in the most diverse fields. Their implementation has led to significant advances in the dermatological cosmetic industry, enabling chemical and molecular screening without animal… Read on PubMed →

Sunless Tanners in Dermatology: A Review of Ingredients, Efficacy, and Safety Profiles.

Journal of drugs in dermatology : JDD · 2026

BACKGROUND: Sunless tanners offer a safer alternative to ultraviolet (UV)-based tanning but may cause adverse skin reactions, including irritant and allergic contact dermatitis. This study examines the composition, efficacy, safety, and reported side effects of commonly used sunless tanning products. METHODS: The top 50 sunless tanners on Amazon's Best Sellers list (March 2025) were reviewed… Read on PubMed →

Ensuring the Safe Use of Bee Products: A Review of Allergic Risks and Management.

International journal of molecular sciences · 2025

Honeybee products (HBPs), including honey, bee pollen, bee bread, royal jelly, propolis, beeswax, and bee brood, are increasingly used in food, nutraceutical, and cosmetic contexts. Because of their natural origin, HBPs can provoke allergic reactions ranging from localised dermatitis to life-threatening, systemic anaphylaxis. As the use of bee products for health purposes grows in apitherapy (a… Read on PubMed →

Double-blind randomised controlled trial of an emollient cream with and without 1 % supercritical CO2 extract of Calendula officinalis in contact dermatitis.

Acta pharmaceutica (Zagreb, Croatia) · 2025

This double-blind randomised controlled trial aimed to evaluate the efficacy of an emollient cream with and without 1 % supercritical CO2 extract of Calendula officinalis in contact dermatitis. Twenty healthy volunteers without pre-existing dermatological conditions participated in this single-centre study. Each participant's forearm was divided into three test sites: control (no treatment)… Read on PubMed →

Authors' Response to Comment on "Patch Testing to Identify Allergens Causing Pigmented Contact Dermatitis: A Retrospective Study".

Indian dermatology online journal · 2026

Successful treatment of poison ivy dermatitis with upadacitinib.

JAAD case reports · 2026

Dermatologists' Perspectives on Skincare Routine Trends.

Clinical, cosmetic and investigational dermatology · 2026

<h4>Background</h4>Multi-step skincare routines have become increasingly popular, particularly among adolescents and young adults, driven by social media exposure and commercial marketing. Although individual skincare ingredients have demonstrated efficacy for specific dermatological conditions, evidence supporting the routine use of elaborate multi-step regimens in otherwise healthy skin remains… Read on PubMed →

Cosmeticorexia: What It Is, Where It Comes from, and Why It Matters.

Dermatology and therapy · 2026

Cosmeticorexia (also called dermorexia) refers to a culturally reinforced preoccupation or obsession with achieving "flawless" skin that can lead to excessive, age-inappropriate, or compulsive use of cosmetic products and procedures. The phenomenon is intensified by the medicalization of beauty, the growth of "cosmeceutical" markets, and social media platforms that reward routine-based content and… Read on PubMed →

Excited Skin Syndrome (Angry Back), What Do We Know About It? A Review of the Literature.

Journal of cosmetic dermatology · 2026

<h4>Background</h4>In 1975, Mitchell brought up a theory that false positive reactions can be due to skin hyperirritability, called it "angry back syndrome" (ABS). The phenomenon is observed in patch testing of patients with several positive patch tests, mostly along with one or more strong reactions. Later, Maibach rephrased ABS to "excited skin syndrome" (ESS) because of generalized involvement… Read on PubMed →

Correction to 'Contact Sensitization to Fragrance Mix I and Fragrance Mix II Among European Dermatitis Patients: A Systematic Review'.

Contact dermatitis · 2026