Research
Latest published research we're tracking.
The newest skincare and haircare papers from PubMed, linked to the ingredients we decode. Summaries are the authors' own abstracts — we excerpt, attribute, and link out to the source.
120 papers under Pregnancy
Pregnancy and risk of melanoma: a matched retrospective cohort study.
Melanoma research · 2026
Pregnancy-associated melanoma has long been debated, with hypotheses that gestational immune tolerance and elevated sex hormones may promote melanocytic transformation; however, large-scale, real-world evidence remains limited and conflicting. Using the TriNetX Global Collaborative Network, we conducted a retrospective cohort study of pregnant patients with documented first and third trimester… Read on PubMed →
Key Considerations in Evaluating Syphilis Therapeutics.
Sexually transmitted diseases · 2026
For more than 70 years, penicillin has remained the cornerstone of treatment for syphilis. While penicillin remains highly effective, there is a pressing need to develop new therapeutic options driven both by ongoing challenges in the supply of benzathine-benzylpenicillin G (BPG) and the need for therapeutics that are more suitable for use in key populations such as pregnant women and infants. Our… Read on PubMed →
What do we mean by preconception health and preconception care in research and policy? A systematic review.
Human reproduction update · 2026
BACKGROUND: Preconception health (PCH) is a globally accepted strategy to reduce preventable adverse pregnancy outcomes and ultimately improve the health of the unborn child. Optimal PCH can be achieved through preconception care (PCC), which encompasses the behavioural, biomedical, and social interventions women and couples undertake and/or receive before conception. However, there is a lack of… Read on PubMed →
Clinical Characteristics and Diagnostic Markers of Genital Varicella-zoster in Women: A 12-year Retrospective Cohort.
Journal of lower genital tract disease · 2026
BACKGROUND: Genital involvement in varicella-zoster virus (VZV) reactivation is uncommon and frequently misdiagnosed. Data on the clinical features of genital zoster are limited, particularly among female patients. METHODS: We conducted a retrospective case series of female patients with genital involvement by VZV at a tertiary referral center between 2013 and 2025. Inclusion required polymerase… Read on PubMed →
The effect of amniotic membrane application on post-cesarean wound healing and cosmetic outcomes.
Scientific reports · 2026
Post-cesarean wound complications-such as surgical site infection (SSI), dehiscence, and hypertrophic scarring-remain a challenge in obstetric surgery. We evaluated whether intraoperative autologous amniotic membrane application improves postoperative outcomes. In a single-blind, randomized controlled trial, 372 women undergoing elective cesarean section were allocated to an amniotic membrane… Read on PubMed →
Aspects of Adverse Effects of Cosmetic Products: An Invited Narrative Review.
Acta dermato-venereologica · 2026
The use of cosmetic products is ubiquitous around the world. This article reviews the medical literature documenting adverse effects associated with cosmetic product use. An extensive, nonexhaustive literature search was conducted using the PubMed database. Studies reporting adverse effects from cosmetic products were included, encompassing case reports, case series, clinical trials and… Read on PubMed →
Oscillometric blood pressure values in infants at 3, 6 and 12 months of age: a cohort study.
BMJ paediatrics open · 2026
OBJECTIVE: To determine reference blood pressure (BP) values in a cohort of healthy infants at 3, 6 and 12 months of age. DESIGN: An antenatally recruited population-based mother-child cohort study. SETTING: The multicentre Preventing Atopic Dermatitis and ALLergies in children study, recruiting non-selected pregnant women in Norway and Sweden between 2014 and 2016. Infant oscillometric BP was… Read on PubMed →
Diverse Methodologies Used for Preclinical Research into Prenatal Cannabis Exposure.
Journal of visualized experiments : JoVE · 2026
The legalization of cannabis across the United States has led to an increase in human use, especially amongst pregnant individuals, driving the need for vigorous scientific investigation on potential health effects to the individual and developing fetuses. Preclinical research, particularly including trans-delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), offers exciting opportunities and… Read on PubMed →
Defective Trophoblast Differentiation, Endothelial Dysfunction, and Immune Dysregulation in Preeclampsia Coalesce on a Placental VGLL3-Centered Gene Network.
Circulation · 2026
BACKGROUND: Preeclampsia affects approximately 1 in 10 pregnancies, leading to severe complications and long-term health risks for both mother and offspring. While the etiology remains unclear, preeclampsia has been linked to both autoimmunity and the timing of menarche. METHODS: Through human single-cell and spatial analyses, coupled with in vitro, in vivo, and ex vivo models, we demonstrate… Read on PubMed →
Impact of advanced wound care methods on obstetric patients: a meta-analysis.
Journal of wound care · 2026
OBJECTIVE: Obstetric procedures, including caesarean sections and episiotomies, often result in surgical wounds requiring effective management to prevent complications. Advanced wound care (AWC) methods-such as bioactive dressings, topical antimicrobials and medicated creams-are increasingly used to enhance healing outcomes. This meta-analysis aimed to quantitatively assess the efficacy of AWC… Read on PubMed →
Deuterated Pentoxifylline Analog in the Treatment of Necrobiosis Lipoidica: A Nonrandomized Clinical Trial.
JAMA dermatology · 2026
IMPORTANCE: Necrobiosis lipoidica (NL) is a rare, chronic granulomatous skin disease for which no US Food and Drug Administration (FDA)-approved treatments exist. PCS499, an oral deuterated pentoxifylline analog, may offer therapeutic benefit. OBJECTIVE: To evaluate the safety and exploratory efficacy of PCS499 in adults with biopsy-confirmed NL. DESIGN, SETTING, AND PARTICIPANTS: A phase 2… Read on PubMed →
Antiseptic Cleansing to Reduce Vertical Transmission of Pathogens to Neonates: The NeoVT-AMR Randomized Clinical Trial.
JAMA network open · 2026
IMPORTANCE: Neonatal sepsis causes substantial mortality. Topical antisepsis for laboring women or neonates may reduce pathogenic colonization and sepsis risk. OBJECTIVE: To evaluate the safety and effectiveness of various topical antiseptic regimens to reduce bacterial load in the maternal genital tract and on neonatal skin and assess suitability for future effectiveness trials. DESIGN… Read on PubMed →
Inflammation Exacerbates Congenital Zika Virus Infection and Naringenin Provides Protective Effects.
Viruses · 2026
Zika virus (ZIKV) infection during pregnancy is a critical driver of Congenital Zika Syndrome (CZS), yet the mechanisms of pathogenesis at the placental barrier remain incompletely understood. This article is a translational, observational, and experimental study combining clinical placental analyses, placental explants cultures and in vivo murine model to investigate the mechanisms involved in… Read on PubMed →
Solitary Rectal Ulcer Syndrome Revisited: A Comprehensive Narrative Review.
Current gastroenterology reports · 2026
PURPOSE OF REVIEW: Solitary rectal ulcer syndrome (SRUS) is a gastrointestinal disorder with a varied range of clinical, endoscopic and histological features. It is often misdiagnosed as inflammatory bowel disease or rectal malignancy. This review aims to outline a practical approach to diagnosing and managing SRUS. RECENT FINDINGS: The aetiology remains unclear, with contributing factors such as… Read on PubMed →
Pregnancy in Women with Atopic Dermatitis: A Systematic Review of Concerns and Challenges.
Acta dermato-venereologica · 2026
Atopic dermatitis (AD) has negative individual and societal implications. However, the potential impact of ADatopic dermatitis on reproduction has only been sporadically investigated. We aimed to provide an overview of pregnancy in ADatopic dermatitis, with a specific focus on concerns, challenges, the number of children, and adverse pregnancy and birth outcomes. A systematic literature search was… Read on PubMed →
Safety of advanced therapies during pregnancy in women with immune-mediated inflammatory diseases: a systematic review and meta-analysis.
Journal of Crohn's & colitis · 2026
BACKGROUND AND AIMS: We aimed to assess the safety of advanced therapies, excluding tumor necrosis factor inhibitors (anti-TNFs), for the treatment of immune-mediated inflammatory diseases (IMIDs), on pregnancy and neonatal outcomes. METHODS AND ANALYSIS: We performed a systematic review and meta-analysis. Study selection and data extraction were conducted independently by two reviewers. Primary… Read on PubMed →
Prevalence of orofacial cleft and its associated factors among newborns in Kembata zone, central Ethiopia 2024.
BMC oral health · 2026
INTRODUCTION: Orofacial clefts are common congenital malformations that impair structural, functional, and psychosocial outcomes. They may be identified at birth or later in life, often requiring surgical correction, which is caused by defects in the integrity and unity of fetal facial structures. These disorders occur between the medial nasal and maxillary processes (cleft lip) and between the… Read on PubMed →
Pre-existing anti-polyethylene glycol antibodies in pregnant women and newborns.
Journal of nanobiotechnology · 2026
Pre-existing anti-polyethylene glycol (PEG) antibodies represent risk factors for reduced efficacy and increased adverse reactions in seropositive individuals, but neither the seropositivities, nor levels nor influencing factors have been investigated in pregnant women or newborns. Herein, maternal and cord blood samples were respectively collected from 256 pregnant women and corresponding 256… Read on PubMed →
CD38 expression by neonatal human naive CD4+ T cells shapes their distinct metabolic and tolerogenic properties.
The Journal of clinical investigation · 2026
Neonatal life is marked by rapid antigen exposure, necessitating establishment of peripheral immune tolerance via conversion of naive CD4+ T cells into Tregs. We demonstrated heightened capacity for FOXP3 expression and tolerogenic function among cord blood versus adult blood naive CD4+ T cells. Further, this was linked to a distinct cord blood metabolic profile and elevated neonatal expression of… Read on PubMed →
Association of Sociodemographics, Healthcare Access, Dental Services and Oral Guidance with Dentifrice Type Used by Preschool Children.
Journal of dentistry for children (Chicago, Ill.) · 2026
Purpose: To evaluate associations between sociodemographic factors, healthcare setting, dental service access and oral health guidance with the type of dentifrice used by preschool children. Methods: Data were collected from available clinical records of children aged 0 to 5 years who had a first visit in a university-based pediatric dental clinic in Rio de Janeiro, Brazil, between 2015 and 2024… Read on PubMed →