Research
Latest published research we're tracking.
The newest skincare and haircare papers from PubMed, linked to the ingredients we decode. Summaries are the authors' own abstracts — we excerpt, attribute, and link out to the source.
141 papers under Baby skin
Fecal tryptophan metabolism predicts the development of infant eczema: a prospective longitudinal study.
Gut microbes · 2026
Early-life microbial metabolism of tryptophan plays a critical role in immune modulation and may influence susceptibility to inflammatory disorders such as eczema. However, longitudinal human data linking microbial tryptophan metabolism to eczema onset are limited. We conducted a prospective cohort study of 40 term-born UK infants, followed from birth to 24 months, stratified by early-onset… Read on PubMed →
Low serum immunoglobulin levels in pediatric atopic dermatitis: association with disease severity and exploratory scores.
European journal of pediatrics · 2026
UNLABELLED: Atopic dermatitis (AD) is a common chronic inflammatory skin disease in childhood. Although low serum immunoglobulin (Ig) levels have been reported in children with AD, their clinical significance and association with disease severity remain insufficiently defined. We aimed to evaluate the association between serum Ig levels and AD severity and to characterize the clinical and… Read on PubMed →
Effectiveness and safety of intranasal fentanyl for pain management in infants aged 0 to 6 months: a systematic review.
JBI evidence synthesis · 2026
OBJECTIVE: The objective of this review was to evaluate the effectiveness and safety of intranasal fentanyl for the management of procedural pain in infants aged 0 to 6 months. INTRODUCTION: Procedural pain in early infancy is frequently undertreated, with limitations in both pharmacological and non-pharmacological interventions. Retinopathy of prematurity screening is a painful procedure for… Read on PubMed →
Safety of dupilumab use during pregnancy: A composite evaluation of pregnancy outcomes.
Allergy and asthma proceedings · 2026
Background: Dupilumab is a monoclonal antibody that targets interleukin 4 and interleukin 13 pathways, increasingly used to treat asthma, eczema, and eosinophilic esophagitis (EoE). Currently, there is minimum literature that evaluated the safety of dupilumab during pregnancy. Objective: This study assessed whether dupilumab use is associated with increased pregnancy complications. Methods: We… Read on PubMed →
Immunoglobulin E-mediated pumpkin seed allergy in children: Case series and narrative review with a structured literature search.
Allergy and asthma proceedings · 2026
Background: Pumpkin seed allergy is a rare but potentially severe immunoglobulin E (IgE) mediated food allergy, with limited pediatric data and few documented cases worldwide. Objective: To describe the clinical and diagnostic characteristics of pediatric pumpkin seed allergy and to synthesize all previously reported cases through a systematically searched narrative review. Methods: We… Read on PubMed →
Key factors in the diagnosis of sesame allergy in children.
Allergy and asthma proceedings · 2026
Background: Sesame allergy (SA) is diagnostically challenging in childhood, and data on its natural course and clinical nonreactivity development are limited. Although oral food challenge (OFC) remains the diagnostic criterion standard, the value of skin-prick tests (SPT) and sesame specific immunoglobulin E (sIgE) in diagnosis and clinical nonreactivity prediction is unclear. Objective: The… Read on PubMed →
Saving the Tiniest Heinies From Diaper Dermatitis in High-Risk Neonates.
Neonatal network : NN · 2026
In 2023, 53% of 300 patients in our NICU developed diaper dermatitis during their hospital stay. Literature indicates that providing effective skin care to patients can help prevent diaper dermatitis. The purpose of this project was to answer the following clinical question: Does application of Cavilon No Sting Barrier with reapplication every 3 days to high-risk newborns, either experiencing… Read on PubMed →
The impact of topical or oral antibiotics in children with acute otitis media on their middle ear, nasopharyngeal, and gut microbiomes.
Epidemiology and infection · 2026
Acute otitis media (AOM) is a major driver of paediatric antibiotic prescriptions. We assessed the impact of oral and topical antibiotics on middle ear, nasopharyngeal, and gut microbiome compositions, and the gut resistome, in children with AOM and ear discharge (AOMd). Fifty-eight children with AOMd and ear pain and/or fever were randomized to oral amoxicillin suspension (n = 31) or… Read on PubMed →
Saccharomycetes and Malassezia fungi associate with early-life gut maturation and allergic disease risk in childhood.
Nature communications · 2026
While early-life gut bacterial microbiota maturation has been well studied and linked to childhood disease, the development of the gut mycobiome remains poorly understood. Few studies have defined fungal succession in infancy, and even fewer have integrated fungal and bacterial maturation, allowing interkingdom analysis within the same individuals. In this study, we analyzed a subset of the CHILD… Read on PubMed →
Atopic dermatitis/eczema phenotypes and their association with food allergy: a nationwide birth cohort study in Japan.
European journal of pediatrics · 2026
UNLABELLED: Atopic dermatitis (AD) is a heterogeneous disease often preceding food allergy (FA). However, it remains unclear how different developmental trajectories of AD/eczema influence the risk of FA. This study aimed to characterize longitudinal AD/eczema phenotypes from infancy to early adolescence and evaluate their specific associations with FA risk. We analyzed data from the Longitudinal… Read on PubMed →
Food introduction during the first year of life in a Swedish birth cohort - associations with allergy at 6 years of age.
Nutrition journal · 2026
BACKGROUND: Diet contains components that may exert broad immunoregulatory properties, including the promotion of tolerance. The timing of food introduction may influence the development of allergies. The aim of this study was to relate the timing of food introduction with doctor's diagnosed allergies (food allergy, atopic eczema, and allergic asthma) at six years of age in a cohort of Swedish… Read on PubMed →
Referral and management patterns for paediatric otorrhoea across primary and secondary care: a multicentre retrospective cohort study.
Primary health care research & development · 2026
AIM: To determine the frequency and nature of referrals for children with acute or chronic otorrhoea from primary care to secondary care ENT services in the UK. BACKGROUND: Middle ear infections in children are common; if the ear drum bursts discharge leaks out (otorrhoea). This causes hearing loss during a critical developmental period. Managing these children in an appropriate time frame to… Read on PubMed →
The modifying role of maternal adverse psychological status on the association between prenatal exposure to per- and polyfluoroalkyl substances and infant atopic dermatitis: A nested case-control study.
Ecotoxicology and environmental safety · 2026
Atopic dermatitis (AD) is a common childhood allergic disease associated with substantial health and economic burdens. Although prenatal exposure to per- and polyfluoroalkyl substances (PFAS) has been linked to adverse child health outcomes, its association with AD and the potential modifying role of maternal adverse psychological status (MAPS) remain unclear. Based on the China National Birth… Read on PubMed →
Skin as a Potential Entry Point for SARS-CoV-2 Virus.
International journal of molecular sciences · 2026
The primary route of SARS-CoV-2 entry is via respiratory epithelium. However, many COVID-19 patients developed dermatological lesions, and SARS-CoV-2 RNA has been detected in the patients' skin. Inflammatory skin diseases, psoriasis and atopic dermatitis (AD), significantly increased the risk of COVID-19. To evaluate the potential role of skin in SARS-CoV-2 host interactions, we utilized 3D human… Read on PubMed →
Results of adjunctive homogenate amniotic membrane eye drops in the management of refractory ocular surface disease with dry eye manifestations.
International ophthalmology · 2026
PURPOSE: To evaluate clinical outcomes of adjunctive treatment with homogenate human amniotic membrane eye drops (AMED) in patients with refractory ocular surface disease with dry eye (DE) manifestations. METHODS: We retrospectively reviewed patients' medical records, ocular surface images, and instrumental data related to Schirmer I test, Oxford and Efron grading, non-invasive tear break-up… Read on PubMed →
Topical application of emollients to maintain skin integrity in preterm neonates: a systematic review and meta-analysis.
European journal of pediatrics · 2026
UNLABELLED: This systematic review and meta-analysis compared the efficacy and safety of topical emollient application in preterm neonates for maintaining skin integrity. The available evidence related to the effects of topical emollients vs. routine skin care was identified, appraised, and synthesized. The outcome measures were assessment of skin integrity, objectively defined by a skin condition… Read on PubMed →
Skin intervention for food allergy prevention: recent advances and clinical implications.
Current opinion in allergy and clinical immunology · 2026
PURPOSE OF REVIEW: Food allergy has increased globally, with infancy representing a critical window for prevention. Accumulating evidence has shifted attention toward the skin as a key route of allergen exposure, particularly in the context of atopic dermatitis. This review is timely given recent advances that have established the dual allergen exposure hypothesis as a clinical paradigm and… Read on PubMed →
Food allergy prevention by early introduction.
Current opinion in allergy and clinical immunology · 2026
PURPOSE OF REVIEW: Food allergy prevalence has increased substantially over the past two decades, particularly for peanut and egg, with significant clinical and psychosocial consequences. Earlier recommendations advocating delayed allergen introduction lacked supporting evidence and may have contributed to this trend. This review summarizes current evidence supporting early allergen introduction… Read on PubMed →
Meteorological, ozone, maternal and individual-level risk factors for childhood diseases in Singapore: A prospective birth cohort study from 2009 to 2019.
Ecotoxicology and environmental safety · 2026
BACKGROUND: The children of today are growing up in an environment characterised by accelerated climate change and air pollution. Few studies have examined the effects of these phenomena on childhood respiratory and allergic diseases in tropical countries, hence we aim to bridge this research gap. METHODS: We ascertained the first occurrence of eczema, wheeze and bronchiolitis in 1124… Read on PubMed →
Pediatric Skin Disease Frequencies and Dermatology Use by Race and Ethnicity in US Children's Hospitals.
JAMA dermatology · 2026
IMPORTANCE: Understanding which children present with skin disease and reach specialty care is essential for characterizing patterns of disease frequency and care use. OBJECTIVE: To describe the frequencies of common pediatric skin diseases and patterns of dermatology use, stratified by race and ethnicity, across 8 US children's hospitals participating in the PEDSnet system. DESIGN, SETTING, AND… Read on PubMed →