Research
Latest published research we're tracking.
The newest skincare and haircare papers from PubMed, linked to the ingredients we decode. Summaries are the authors' own abstracts — we excerpt, attribute, and link out to the source.
7 papers under Malassezia
Antibiotic-induced Malassezia expansion in the infant gut promotes early-life immune dysregulation and airway inflammation in mice.
Nature communications · 2026
Antibiotics have deleterious consequences for the gut microbiome and can increase the risk of childhood asthma. While the effects of antibiotics on the bacterial microbiome and asthma risk are well characterized, their impact on the fungal microbiome (mycobiome) remains vastly unexplored. We investigated the effect of antibiotic use on the gut mycobiome in an observational, prospective clinical… Read on PubMed →
Advances in Scalp Microbiome Research: Molecular Insights into the Metabolism-Inflammation-Barrier Axis and Dandruff Pathogenesis.
Molecules (Basel, Switzerland) · 2026
Dandruff (DF) is a prevalent, recurrent inflammatory scalp disorder increasingly recognized as a complex state of functional dysbiosis rather than a simple Malassezia overcolonization. The scalp microbiome is predominantly shaped by Malassezia species (M. restricta and M. globosa), Cutibacterium, and Staphylococcus species. Recent multi-omics evidence indicates that DF pathogenesis is driven by… Read on PubMed →
Molecular identification and pathogenicity confirmation of multi-azole resistant Malassezia species isolated from dandruff infected individuals prevailing in Mysuru, India.
Diagnostic microbiology and infectious disease · 2026
Worldwide distribution of dandruff associated scalp infections is caused by lipophilic Malassezia spp. This rationale lead the study to investigate the prevalence and etiologic species in a cross-sectional study involving 300 subjects who visited dermatology hospitals to seek treatment in K.R. Hospital, JSS Hospital and CSI Holdsworth Memorial Mission Hospital, Mysuru region, Karnataka, India… Read on PubMed →
Exploring the Skin Mycobiome: A Comparison of Skin Swabs and Tissue Specimens.
Aesthetic plastic surgery · 2026
Recent research has underscored the significant role of skin fungi in human health and disease. The advent of next-generation sequencing has facilitated the identification of previously unrecognized fungi; however, a standardized sampling method for the skin mycobiome has yet to be established. Given that fungi are distributed across all layers of the skin, this study aimed to establish and… Read on PubMed →
Decoding the Skin Micro-Immune Milieu, Homeostasis, and Keratinocyte Trafficking in Psoriatic Disease.
Immunological investigations · 2026
INTRODUCTION: The skin, acting as a complex interface between the immune system and microbiome, maintains balance through coordinated interactions among the epidermal barrier, microbiome, and immune responses. Psoriasis, a chronic autoimmune and inflammatory disorder, disrupts this balance by altering keratinocyte growth, immune signaling, and microbial diversity. RESULTS AND DISCUSSION: The… Read on PubMed →
Cupuaçu (Theobroma grandiflorum) butter nanoparticles associated with oligosaccharides as cosmetic carriers for prebiotic effect: development, physicochemical characterization, and preclinical evaluation.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2026
The skin microbiota is essential for cutaneous homeostasis, and prebiotics may support it. Nanostructured systems, such as cupuaçu-derived nanoparticles, enhance the delivery and stability of cosmetic active substances, but their role in modulating the skin microbiota remains unclear and requires targeted evaluation. In this study, lipid-polymeric hybrid nanoparticles based on cupuaçu (Theobroma… Read on PubMed →
Commensal yeast Malassezia produces tryptophan metabolites to promote tissue homeostasis via the aryl hydrocarbon receptor in mice.
Nature microbiology · 2026
As an abundant fungal colonizer of mammalian skin, Malassezia establishes mutualistic or pathogenic interactions with the host. Here we show that Malassezia furfur promotes skin homeostasis by maintaining epidermal integrity via tryptophan-derived metabolites that activate the aryl hydrocarbon receptor (AhR), a key regulator of keratinocyte differentiation and inflammation. M. furfur-derived… Read on PubMed →