Research
Latest published research we're tracking.
The newest skincare and haircare papers from PubMed, linked to the ingredients we decode. Summaries are the authors' own abstracts — we excerpt, attribute, and link out to the source.
141 papers under Baby skin
Emollients to Prevent Pediatric Eczema: A Randomized Clinical Trial.
JAMA dermatology · 2025
<h4>Importance</h4>Atopic dermatitis (AD) imposes a global health burden for children and is a risk factor for developing food allergy and asthma. Few studies have evaluated emollient intervention for primary AD prevention in infants not selected for risk.<h4>Objective</h4>To determine whether emollient intervention in infants not selected for risk reduces AD incidence by age 24 months.<h4>Design… Read on PubMed →
Early Neonatal Death in Harlequin Ichthyosis: A Case Report and Literature Review.
Clinical case reports · 2025
Harlequin ichthyosis is a rare, life-threatening neonatal disorder often mistaken for collodion baby. We report a 37-week neonate with severe ectropion, eclabium, and thick fissured scales who died on Day 2 despite optimal care. This case highlights the diagnostic challenges, intensive management needs, and poor prognosis of Harlequin ichthyosis. Read on PubMed →
Clinical Evaluation of a Diaper Containing a Shea Butter-Based Emollient and Impact on Diapered Skin Erythema.
Pediatric dermatology · 2025
<h4>Background/objectives</h4>Skin is a baby's first line of defense against mechanical, chemical, enzymatic, and microbial insults. Preventive interventions in the diapered area are important given repetitive, episodic exposures to irritants in urine and feces. For over a century, physicians have utilized petrolatum-based emollients (PBE) prophylactically and retroactively for skin irritation in… Read on PubMed →
Skin Care Practices in Indian Newborns and Infants: Current Scenario.
Pediatric health, medicine and therapeutics · 2025
Compared to adults, the skin of newborns and infants is more prone to trauma and infection and requires appropriate care for proper maturation and function. Efforts are ongoing to comprehend how skin care practices and products affect the healthy development of newborn skin. The situation in India is more difficult because newborns and infants' skin is often treated with both conventional and… Read on PubMed →
Prevention of Atopic Dermatitis: What Are We Missing?
Allergy, asthma & immunology research · 2025
Atopic dermatitis (AD) is a prevalent chronic inflammatory disease that significantly burdens individuals and healthcare systems worldwide. The incidence of AD has risen sharply in both developed and emerging economies, necessitating an understanding of its complex etiological factors, including environmental influences and lifestyle changes. Generally, 2 primary preventive strategies for AD have… Read on PubMed →
Clinical Benefits of Basic Emollient Therapy for the Management of Patients With Xerosis Cutis.
International journal of dermatology · 2025
Xerosis cutis refers to dry skin that may be caused or exacerbated by external triggers (e.g., cold weather), endogenous factors (e.g., aging), or present as a symptom of other diseases (e.g., atopic dermatitis). Emollients are topical products formulated to rehydrate and restore the barrier function of the skin and are consistently recommended for the management of xerosis cutis and related… Read on PubMed →
Revisiting the Etiology and Management of Atopic Dermatitis: A Perspective on Skin Microbiota, Bathing Habits, and Surfactant-Free Skincare.
Clinical, cosmetic and investigational dermatology · 2025
The current consensus on the pathophysiology of atopic dermatitis (AD) involves Th2/Th22 inflammation, genetic predisposition such as filaggrin mutations, and skin barrier dysfunction. Meanwhile, AD has been hypothesized to be primarily caused by the defective formation of the commensal microbial community with insufficient skin regeneration as a secondary aggravating factor. AD presents with… Read on PubMed →
Harlequin Ichthyosis in a Preterm Neonate: A Case Report.
Cureus · 2025
Harlequin ichthyosis is a rare autosomal recessive disorder characterized by severe hyperkeratosis and impaired skin barrier function, often associated with high neonatal mortality. We present the case of a preterm neonate born by cesarean section at 32 weeks of gestation with classical features of Harlequin ichthyosis, confirmed by genetic testing. Despite intensive neonatal and dermatologic… Read on PubMed →
Netherton Syndrome: A Systematic Review of the Challenges of Diagnosis and Treatment.
Cureus · 2025
Netherton syndrome is an autosomal recessive genodermatosis caused by biallelic mutations in the SPINK5 gene, a gene that codes for lymphoepithelial Kazal-type-related inhibitor 1 (LEKT1) protein. This disorder is characterized by erythroderma, ichthyosis, hair shaft abnormalities, and immune dysregulation. While there is increasing research and recognition of Netherton syndrome, much remains… Read on PubMed →
Skin barrier as a target for the prediction, prevention, and treatment of atopic dermatitis and food allergy in infancy.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
Atopic dermatitis (AD) and food allergy (FA) frequently manifest during infancy and share skin barrier dysfunction as a critical early pathogenic event. Recent research has elucidated structural, lipidomic, microbial, and immunologic abnormalities that compromise the skin barrier and contribute to disease onset. Filaggrin gene mutations, altered ceramide profiles, and type 2 cytokine-driven… Read on PubMed →
Neonatal Erythroderma: Diagnostic Challenges and the Limitations of Genetic Testing.
Cureus · 2025
Neonatal erythroderma (NE) is an uncommon but serious presentation characterised by generalised erythema and scaling from birth. Its aetiology is diverse, encompassing congenital ichthyoses, infections, metabolic disorders, immunodeficiencies, and syndromic causes. We report the case of a full-term male neonate presenting shortly after birth with diffuse erythema, fine scaling, and areas of skin… Read on PubMed →
Indian academy of pediatrics (neonatology chapter) recommendations for evidence-based neonatal skincare and protocols for hospitalized neonates.
Frontiers in pediatrics · 2025
<h4>Introduction</h4>Infants in a neonatal intensive care unit (NICU) face a significant risk of skin barrier damage due to various factors related to their condition and the medical interventions they receive. The Neonatology Chapter of the Indian Academy of Pediatrics aimed to develop a comprehensive guidance document on evidence-based clinical practices for neonatal skin care in hospitalized… Read on PubMed →
Probiotics and human health: biological activities, nutritional aspects, immunomodulatory properties, applications, and future perspectives - a comprehensive review.
Frontiers in immunology · 2025
Probiotics, defined as living microorganisms, are widely recognized for their ability to positively influence the gut microbiota, an effect increasingly linked to a wide array of health benefits. They are claimed to treat or prevent conditions ranging from infant colic to cardiovascular disease, respiratory infections, and certain cancers. Since the beginning of the 21st century, consumer demand… Read on PubMed →
Early skin inflammatory biomarker is predictive of development and persistence of atopic dermatitis in infants.
The Journal of allergy and clinical immunology · 2024
<h4>Background</h4>The Short-Term Topical Application for Prevention of Atopic Dermatitis (STOP AD) study, a randomized, open-label trial evaluating the effect of short-term (from the first 4 postnatal days to age 8 weeks) skin barrier protection using Aveeno Dermexa Fast & Long-Lasting Balm (Johnson & Johnson, New Brunswick, NJ) in infants with a parent with allergic disease, demonstrated… Read on PubMed →
Should Emollients Be Recommended for the Prevention of Atopic Dermatitis?-New Evidence and Current State of Knowledge.
Journal of clinical medicine · 2024
<h4>Introduction</h4>Atopic dermatitis (AD) is a chronic, pruritic skin disease with complex pathogenesis, which affects about 43 million children aged 1-4 years. One of the most known methods of alleviating symptoms of AD is emollient treatment, which varies depending on formulation and additional active ingredients. There is some evidence that emollients could be used in AD prevention in… Read on PubMed →
Skin-centered strategies in food allergy prevention.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2024
While the early introduction of food allergens in the infant diet has been shown to be effective at preventing the development of food allergy (FA), its implementation in real life has been associated with various challenges. Interventions aimed at correcting skin barrier dysfunction have been explored in recent decades as a distinct or complementary mean to prevent allergic sensitization through… Read on PubMed →
Atopic dermatitis.
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024
Atopic dermatitis (AD) is a common, chronic skin disorder that can significantly impact the quality of life (QoL) of affected individuals as well as their families. Although the pathogenesis of the disorder is not yet completely understood, it appears to result from the complex interplay between defects in skin barrier function, environmental and infectious agents, and immune dysregulation. There… Read on PubMed →
Skin microbiota: pathogenic roles and implications in atopic dermatitis.
Frontiers in cellular and infection microbiology · 2024
Atopic dermatitis (AD) is a chronic and inflammatory skin disorder characterized by impaired barrier function and imbalanced immunity. Recent advances have revealed that dysbiosis of skin microbiota plays important roles in the pathogenesis and development of AD. Meanwhile, endogenous and external factors contribute to the dysbiosis of skin microbiota in AD. Additionally, various treatments… Read on PubMed →
Managing the Skin Microbiome as a New Bacteriotherapy for Inflammatory Atopic Dermatitis.
Cureus · 2023
The microbiome, comprising various bacteria, assumes a significant role in the immune system's maturation and maintaining bodily homeostasis. Alterations in the microbial composition can contribute to the initiation and progression of inflammation. Recent studies reveal that changes in microbial composition and function, known as dysbiosis in the skin and gut, have been associated with altered… Read on PubMed →