Latest published research we're tracking.

RIFM fragrance ingredient safety assessment, ethyl palmitate, CAS Registry Number 628-97-7.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2026

Ethyl palmitate was evaluated for genotoxicity, repeated dose toxicity, reproductive toxicity, local respiratory toxicity, photoirritation/photoallergenicity, skin sensitization, and environmental safety. Data from read-across analogs methyl hexadecanoate (CAS # 112-39-0) and methyl decanoate (CAS # 110-42-9) show that ethyl palmitate is not expected to be genotoxic. Data on read-across analog… Read on PubMed →

Delgocitinib cream for adolescents with moderate to severe chronic hand eczema (DELTA TEEN): a multicentre, double-blind, phase 3 randomised controlled trial.

The Lancet. Child & adolescent health · 2026

BACKGROUND: Chronic hand eczema is a multifactorial, inflammatory skin disease associated with itch, pain, and a substantial physical and psychosocial burden. Delgocitinib cream (2%, 20 mg/g), a topical, non-steroidal, pan-Janus kinase inhibitor, is approved for the treatment of moderate to severe chronic hand eczema in adults. We aimed to assess the efficacy and safety of delgocitinib cream in… Read on PubMed →

Cosmetic Allergies: Use of Patch Testing and Molecular Diagnostics to Identify Allergic Responses.

Plastic and aesthetic nursing · 2026

I investigated the key causes and mechanisms of skin sensitization, evaluated existing diagnostic methods, and proposed new strategies to reduce the risk for allergic reactions. My research focused on sensitization to cosmetic components, including synthetic fragrances, preservatives (i.e., methylisothiazolinone, chlorphenesin), and natural extracts. I used patch testing and molecular diagnostics… Read on PubMed →

Delayed Re-epithelialization Following Full-Field Er:YAG Laser Resurfacing: A Case Report.

Cureus · 2025

Full-field erbium-doped yttrium aluminum garnet (Er:YAG) laser resurfacing is widely used for photoaging and scars, with re-epithelialization expected within five to seven days. Delayed healing is uncommon and may result from infection, inappropriate wound care, or allergic contact dermatitis (ACD). We present a 32-year-old woman who underwent full-face Er:YAG resurfacing (fluence: 8 J/cm², pulse… Read on PubMed →

Epidemiological profile and main allergens identified in cases of allergic contact cheilitis.

Anais brasileiros de dermatologia · 2025

Not Just Pink Eye: Allergic Contact Dermatitis to Alcaftadine 0.25% Ophthalmic Solution.

Contact dermatitis · 2025

Prevalence of Contact Allergy to Propolis-Testing With Different Propolis Patch Test Materials.

Contact dermatitis · 2025

<h4>Introduction</h4>Propolis is a sticky substance produced by honeybees from plant resins collected from locally growing vegetation. Its chemical composition varies depending on the plant species visited by the bees. Contact dermatitis is commonly reported following exposure to cosmetics containing propolis or following the intake of food supplements.<h4>Objectives</h4>To investigate the… Read on PubMed →

The impact of perfumes and cosmetic products on human health: a narrative review.

Frontiers in toxicology · 2025

<h4>Background</h4>The use of perfumes and cosmetic products is widespread, serving personal hygiene, aesthetic, and olfactory functions. However, concerns have been raised regarding the potential health impacts associated with long-term exposure to various ingredients used in these products.<h4>Objectives</h4>This narrative review aims to synthesize evidence on the health risks associated with… Read on PubMed →

Patch Test Preparations: Basis and State-of-the-Art Modern Diagnostic Tools for Contact Allergy.

Journal of clinical medicine · 2025

Reliable quality of epicutaneous patch test (PT) preparations is a prerequisite for establishing a robust diagnosis in patients with suspected allergic contact dermatitis due to delayed-type sensitization. It is difficult to identify potential quality issues in daily practice, since confirmatory methods are lacking and assessment of PT-relevance is predominantly based on patients' history and… Read on PubMed →

A Multi-Center Study on Sensitization to Thimerosal in North-Eastern Italy, 1997-2023: Prevalence, Risk Factors, the Role of Occupation and the Impact of Vaccinations.

Vaccines · 2025

<b>Background</b>: Thimerosal has been widely used as a preservative to prevent microbial growth in medications and vaccines. However, in 1999 its removal from vaccine formulations was called for due to concerns about its potential side effects on humans, with subsequent reduced sensitizations at patch tests. The present multi-center study investigated the epidemiological, occupational and… Read on PubMed →

Elucidating the Relationship Between Mycosis Fungoides and Contact Sensitization: A Retrospective Study.

Dermatitis : contact, atopic, occupational, drug · 2025

<u><b></b></u> <u><b><i>Background:</i></b></u> Mycosis fungoides (MF), a type of cutaneous T cell lymphoma (CTCL), presents diagnostic challenges due to its complex etiology. Previous studies suggest a link between MF and type IV hypersensitivity, particularly allergic contact dermatitis (CD), but conclusive evidence is lacking. <u><b><i>Objective:</i></b></u> To investigate the relationship… Read on PubMed →

Hair Products Marketed to Adolescents on Social Media: A Cross-Sectional Study.

Skin appendage disorders · 2025

<h4>Introduction</h4>Social media is widely used by adolescents and hair products are frequently promoted on these platforms. However, little is known about marketing strategies or potential dermatologic risks.<h4>Methods</h4>We analyzed the first 100 TikTok and 50 Instagram posts using the hashtags "#teenhaircare," "#tweenhaircare," and "#hairtok" (10/05/2025-10/15/2025). Eligible posts were… Read on PubMed →

Allergic Contact Dermatitis of the Vulva.

Contact dermatitis · 2025

<h4>Background</h4>While previous studies have investigated allergic contact dermatitis (ACD) in patients with chronic vulvar complaints, data on the clinical relevance of patch test results, particularly from spices and herbs series, remain limited.<h4>Objectives</h4>To determine the frequency and clinical relevance of contact sensitisation to allergens in the European Baseline Series (EBS) and a… Read on PubMed →

Eyelid Allergic Contact Dermatitis Caused by Nickel From a Surprising Source: An Illustrating Case of Illuminating Eye Care.

Contact dermatitis · 2025

Severe Allergic Contact Dermatitis From Octylisothiazolinone in Over-Ear Headphones: A Case Series.

Contact dermatitis · 2025

<h4>Background</h4>Octylisothiazolinone (OIT; CAS 26530-20-1) is used as a biocide in leather products.<h4>Objectives</h4>To report several cases of allergic contact dermatitis (ACD) from the use of headphones containing OIT, and to highlight the strong allergic potential of this preservative.<h4>Patients and methods</h4>Four patients with ACD from headphones were patched tested using the European… Read on PubMed →

Sodium Benzoate as an Emerging but Problematic Allergen: Retrospective Analysis of Patch Test Results in 3198 Cases Underlines the Need for an Improved Test Preparation, as Even Dubious Reactions May Be Clinically Relevant.

Contact dermatitis · 2025

<h4>Background</h4>Sodium benzoate is increasingly used as a preservative in personal care products and in foods. Recently published experience of patch testing sodium benzoate at 5% in pet shows it to be an allergen that may be assuming increasing clinical relevance.<h4>Objectives</h4>We set out to define the prevalence of clinically relevant reactions to sodium benzoate, to delineate problems… Read on PubMed →

Caprylhydroxamic Acid: A Growing Allergen in Skincare Products.

Contact dermatitis · 2025

Potential Allergens in Medical Adhesives in Tapes, Wound Dressings, and Ostomy Care: A Scoping Review.

Contact dermatitis · 2025

<h4>Background</h4>Medical adhesives are increasingly reported, although still underestimated as causes of allergic contact dermatitis, for which identification of the sensitising culprits is often impossible, mainly because of non-declaration of components on medical device packaging and lack of cooperation from manufacturers.<h4>Objectives</h4>To report on the allergens identified in medical… Read on PubMed →

Eyelid Contact Dermatitis: 25-Year Single-Center Retrospective Study.

Journal of clinical medicine · 2025

<b>Background/Objectives</b>: Eyelid dermatitis is an inflammatory disease affecting the palpebral skin characterized by itching, edema, and scaling of the periorbital area. This entity can be a manifestation of various underlying dermatological diseases, but allergic contact dermatitis (ACD) is the predominant etiology of eyelid dermatitis among patients, being diagnosed in 43.4% of cases. The… Read on PubMed →

Contact Allergy in Atopic Dermatitis and Psoriasis: A Retrospective Study.

Diagnostics (Basel, Switzerland) · 2025

<b>Background/Objectives</b>: The correlation between contact allergy (CA), atopic dermatitis (AD) and psoriasis is still debated. Therefore, the present study aims to retrospectively analyze the frequency of contact sensitization among patients with psoriasis and AD compared to controls, in order to further investigate the relationship between CA and the underlying immunological background… Read on PubMed →