Latest published research we're tracking.

Consultations, prescribed topical treatments and disease severity in children with eczema in primary care: analysis of electronic medical records in the BATHE study.

Clinical and experimental dermatology · 2026

<h4>Background</h4>In countries with well-resourced primary care, most children with eczema are managed by their general practitioner, but we know little about how often they are seen or how they are treated.<h4>Objectives</h4>To describe patterns of consultations and prescribing by eczema severity for children with eczema.<h4>Methods</h4>Analysis of electronic medical record data from 422… Read on PubMed →

Dysbiosis in the Pathogenesis of Atopic Dermatitis.

The Journal of dermatology · 2026

Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by epidermal barrier dysfunction and immune dysregulation. Recent research highlights cutaneous dysbiosis as a critical factor in its pathogenesis. In this review, we summarize the interplay between the skin microbiota and host immunity, contrasting the homeostatic state with the dysbiosis in AD. In healthy skin, resident… Read on PubMed →

Skin pain in pediatric atopic dermatitis: mechanisms and management.

Current opinion in allergy and clinical immunology · 2026

<h4>Purpose of review</h4>While itch is the hallmark symptom of atopic dermatitis (AD), skin pain is increasingly recognized as a common and burdensome symptom even in the pediatric population. Despite its prevalence, pain remains underassessed and undertreated in children with AD. This review aims to synthesize current knowledge on the prevalence, pathophysiology, clinical relevance, and… Read on PubMed →

Neonatal Netherton syndrome: Dermoscopic clues for early diagnosis.

JAAD case reports · 2026

Current skin care practices in very low birth weight infants in German Neonatal Intensive Care Units - results from a cross-sectional survey.

Molecular and cellular pediatrics · 2026

<h4>Background</h4>The skin is the largest epithelial organ and a critical barrier. However, in preterm infants, particularly very low birth weight infants (VLBWI, < 1500 g), it is immature and highly susceptible to injury and infection. Despite growing awareness of neonatal skin care, evidence-based guidelines for this vulnerable population are lacking. This study aimed to provide an overview of… Read on PubMed →

Atopic Comorbidities and Topical Steroids in Early Childhood Atopic Dermatitis: Are We Missing a Piece of the Puzzle?

Clinical reviews in allergy & immunology · 2026

Topical corticosteroids (TCS) remain the first-line treatment for (AD). This narrative review examines clinical data on the immunomodulatory effects of TCS and recent treatments for atopic dermatitis (AD) in early childhood in the context of atopic comorbidities. While TCS are effective in reducing several markers of inflammation in infants with AD, certain type 2 cytokines, such as interleukin… Read on PubMed →

Enhanced Recovery of the Barrier of Compromised Skin with pH-Buffered Emollient Baby Wipes.

Sage open pediatrics · 2026

<h4>Aim</h4>This study aimed to investigate the impact of different types of baby wipes on the barrier recovery of compromised skin after repeated wiping.<h4>Methods</h4>The forearm skin of adult females was compromised through repeated tape-stripping. Baby wipes with different compositions and water and cloth were used to repeatedly wipe the compromised forearm skin. The health of the skin… Read on PubMed →

Enteral Green Beans in the Management of Neonatal Irritant Diaper Dermatitis.

Pediatric dermatology · 2026

Irritant diaper dermatitis (IDD) is frequently observed in neonatal intensive care units and is often exacerbated by chronic loose stools. Despite standard treatments, erosive or persistent IDD remains challenging to manage. We introduced pureed green beans into enteral feeds as a source of fiber to improve stool consistency and reduce skin breakdown. This intervention has been highly effective as… Read on PubMed →

Feeding the Skin? Foods in Personal Care Products and the Risk of Allergy.

The Journal of clinical and aesthetic dermatology · 2026

The interrupted skin barrier seen in atopic dermatitis (AD) increases exposure to environmental antigens including those in food, which contributes to the increased prevalence of food allergies in the AD population. This relationship is further explored in the dual allergen exposure hypothesis, which examines the differences in immune system response between cutaneous and oral exposures. It was… Read on PubMed →

Systemic Salicylate Toxicity From Topical Emollient Use in an Infant With Suspected Ichthyosis.

Cureus · 2026

We report a case of a six-month-old female infant weighing 4.56 kg who presented with altered mental status, severe metabolic acidosis, and multiorgan dysfunction following chronic use of an over-the-counter topical cream containing salicylic acid. The patient had a longstanding pruritic rash treated at home with multiple daily applications of the same topical salicylic acid-containing cream. She… Read on PubMed →

Safety of Ferric Citrate Hydrate in Pregnant Women With Iron Deficiency Anemia, Fetuses, and Newborns: A Real-World, Observational, Post-Marketing Surveillance Study.

The journal of obstetrics and gynaecology research · 2026

AIM: This post-marketing surveillance study determined the real-world use and safety of ferric citrate hydrate (FC) in fetuses and pregnant women with iron deficiency anemia (IDA). METHODS: Pregnant women with IDA were registered centrally and followed prospectively from the first FC administration until the end of pregnancy or at treatment discontinuation. Demographic characteristics, FC… Read on PubMed →

Topical steroids are effective even in severe phimosis: Evidence from a multicenter cohort.

Journal of pediatric surgery · 2026

Phimosis is commonly encountered in pediatric surgical practice. Despite evidence supporting topical corticosteroids for phimosis, many clinicians believe they are ineffective in certain subgroups such as severe phimosis or older children, leading to early circumcision. This study aimed to evaluate the effectiveness of topical corticosteroids across different severities and patient… Read on PubMed →

Serum Proteomic Profiling Uncovers Dysregulated Keratinisation and Immune-Related Pathways in Hidradenitis Suppurativa.

Experimental dermatology · 2026

Hidradenitis suppurativa (HS) is an autoinflammatory keratinisation disease affecting the pilosebaceous unit and hallmarked by a complex and multifactorial pathogenesis. Although genomic and transcriptomic investigations have substantially advanced our understanding of key mechanisms underlying HS pathogenesis, proteomic studies remain limited, despite the significant potential of serum proteomics… Read on PubMed →

Neighborhood Disadvantage Lacks Correlation With Delayed Orchiopexy for Congenital Cryptorchidism.

The Journal of surgical research · 2026

INTRODUCTION: Orchiopexy for congenital cryptorchidism is ideally performed by 18 mo of age to optimize patient outcomes. This study aims to determine whether surrogates for neighborhood disadvantage-Social Vulnerability Index (SVI) and Area Deprivation Index (ADI)-correlate with risk for delayed orchiopexy. METHODS: We conducted a retrospective cohort study at a single tertiary care pediatric… Read on PubMed →

The association between polyunsaturated fatty acids in breast milk and infant eczema and its relationship with infant gut microbiota.

Asia Pacific journal of clinical nutrition · 2026

BACKGROUND AND OBJECTIVES: Current evidence on the relationship between breast milk fatty acids and infant eczema is limited. The present study aimed to investigate the association between polyunsaturated fatty acids (PUFAs) in breast milk and the incidence of infant eczema and its relationship with infant gut microbiota. METHODS AND STUDY DESIGN: Twenty-five infants diagnosed with eczema and… Read on PubMed →

Safety and Efficacy of Treatment with Dupilumab for up to 2 Years in Infants and Young Children with Atopic Dermatitis.

American journal of clinical dermatology · 2026

BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory disease with a high clinical burden and risk of persistence in pediatric patients. OBJECTIVE: To assess safety and efficacy of treatment with dupilumab for up to 2 years in infants and young children with AD. METHODS: Patients aged 6 months to 5 years who had previously participated in parent studies LIBERTY AD PRESCHOOL Part A or B… Read on PubMed →

Safety of Topical Epinephrine Compared with Oxymetazoline in Pediatric Functional Endoscopic Sinus Surgery: A Retrospective Cohort Study.

The Annals of otology, rhinology, and laryngology · 2026

OBJECTIVE: To assess the safety of topical epinephrine during pediatric functional endoscopic sinus surgery (FESS). METHODS: After obtaining IRB approval, electronic medical records of patients aged 0 to 14 undergoing FESS in 2021 were retrospectively reviewed and divided into 2 cohorts based on the topical vasoconstrictive agent utilized during the case: oxymetazoline or epinephrine. Patients… Read on PubMed →

Serum TARC Levels Reflect the Severity and Prognosis of Atopic Dermatitis in Infants Under 6 Months of Age: A Retrospective Study in a Pediatric Primary Care Practice.

The Journal of dermatology · 2026

This study evaluated the clinical utility of serum TARC levels as an objective biomarker in infants with atopic dermatitis (AD) under 6 months of age in pediatric primary care practice, a population for which evidence remains limited. A retrospective search identified 61 infants (median age: 4 months) diagnosed with AD using The UK Working Party criteria and the Japanese guidelines for atopic… Read on PubMed →

Long-Term Safety and Efficacy of Dupilumab Treatment in Children Aged 6 Months to 5 Years with Severe Atopic Dermatitis.

Paediatric drugs · 2026

BACKGROUND: Infants and young children with severe atopic dermatitis (AD) have a high burden of disease with a strong impact on quality of life. Here we assess long-term efficacy and safety of dupilumab in pediatric patients aged 6 months to 5 years with severe AD. METHODS: This is a subgroup analysis of patients aged 6 months to 5 years enrolled in the ongoing LIBERTY AD PED open-label extension… Read on PubMed →

Residential greenness and atopic dermatitis in Japanese children: Findings from the TMM BirThree cohort study.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026

BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin disease that primarily develops during childhood. Residential greenness has been reported to be associated with AD onset. However, findings are inconsistent and may not apply to Japanese settings because vegetation and residential environments vary regionally. Therefore, this study aimed to examine early-life exposure to residential… Read on PubMed →