Research
Latest published research we're tracking.
The newest skincare and haircare papers from PubMed, linked to the ingredients we decode. Summaries are the authors' own abstracts — we excerpt, attribute, and link out to the source.
374 papers
Malassezia Folliculitis Presentation, Diagnosis, and Treatment: A Review of "Fungal Acne".
Journal of drugs in dermatology : JDD · 2026
BACKGROUND: Malassezia folliculitis (MF), commonly referred to as "fungal acne" is a dermatological condition caused by colonization of the commensal fungus Malassezia, which turns pathogenic under certain conditions. MF presents as pruritic, erythematous papules and pustules and is often mistaken for other dermatological conditions, including acne vulgaris (AV). Interest in MF has intensified in… Read on PubMed →
Sulforaphane in Cutaneous Disorders and Skin Injury: Mechanisms, Evidence, and Clinical Perspectives.
Nutrients · 2026
Cutaneous disorders such as atopic dermatitis, psoriasis, acne vulgaris, and rosacea, together with UV-induced skin injury and photoaging, are highly prevalent conditions that involve varying contributions from dysregulated immune responses, cutaneous inflammation, oxidative stress, barrier dysfunction, microbiome alteration, and exogenous injury. However, these conditions are biologically… Read on PubMed →
Routine blood monitoring in acne vulgaris patients on isotretinoin: Is reassessment warranted? A retrospective cohort study from Tygerberg Hospital.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde · 2026
BACKGROUND: Oral isotretinoin is an indispensable treatment for patients with resistant and severe acne vulgaris, both in South Africa (SA) and globally. While routine laboratory monitoring is often deemed unnecessary for young, healthy patients, it remains unclear whether this applies in the SA context. OBJECTIVES: To assess the need for routine blood monitoring for acne vulgaris patients on… Read on PubMed →
ROS-Responsive Hydrogel Delivering Bio-Nanoselenium for Targeted Therapy of UVB-Induced Skin Photodamage.
ACS applied materials & interfaces · 2026
Ultraviolet B (UVB) radiation is a major environmental factor that induces skin photodamage through oxidative stress and inflammation. To address this, we developed a reactive oxygen species (ROS)-responsive hydrogel, SeNPs@HPTA, for the intelligent delivery of biogenic selenium nanoparticles (BioSeNPs) synthesized by Bifidobacterium animalis. The hydrogel was fabricated by cross-linking… Read on PubMed →
Effectiveness of omega-3 poly unsaturated fatty acids on the treatment of gingival hyperpigmentation: a randomized controlled clinical trial.
BMC oral health · 2026
BACKGROUND: In dentistry, gingival hyperpigmentation is a common aesthetic issue caused mainly by excessive melanin deposits. Traditional surgical methods for depigmentation, like surgical techniques, can be effective, but they often associated with pain after the procedure and longer healing times. Because of their anti-inflammatory and antioxidant qualities, omega-3 polyunsaturated fatty acids… Read on PubMed →
Comparison of the Burden of Acne Vulgaris in China vs Globally: Insights from the Global Burden of Disease Study (2021) and Projections to 2050.
Acta dermato-venereologica · 2026
Acne vulgaris (AV) poses a significant health challenge in China, adversely affecting patients' quality of life and mental health. Updated evidence on acne burden in China integrating temporal trends, China-global comparisons, change-point patterns, and future projections remains limited. This study aimed to provide an updated assessment of AVacne vulgaris burden in China, including temporal… Read on PubMed →
Oral myo-inositol plus D-chiro-inositol (3.6:1) reduces insulin resistance pathway biomarkers in acne-involved skin among subjects with metabolic comorbidities: A gene expression study.
Neuro endocrinology letters · 2026
BACKGROUND: Hyperinsulinemia and insulin resistance promote acne pathogenesis through reduced Forkhead box protein O1 (FOXO1) signaling and increased mechanistic target of rapamycin (MTOR) and insulin-like growth factor-1 (IGF1) activity. While oral myo-inositol (MI) and D-chiro-inositol (DCI) supplementation may improve insulin sensitivity, evidence regarding direct pathway modulation in… Read on PubMed →
Sun Protection Behaviours and Photosensitivity in Japanese Children: Toyama Adjunct Study of Japan Environment and Children's Study (JECS).
Acta dermato-venereologica · 2026
Children have up to three3 times the annual sun exposure of adults. This cross-sectional study evaluated sun protection behaviorbehaviour, related factors, and the incidence of photosensitivity in Japanese children. A self-administered questionnaire administered to mothers of second2nd-grade children as part of the Toyama Adjunct Study of the Japan Environment and Children's Study was used and… Read on PubMed →
Mechanistic Insights Into the Photosensitizing Properties of the Topical Retinoid Tazarotene.
ChemMedChem · 2026
Since the FDA approval of tretinoin in 1971, retinoids have been key in treating acne and different skin pathologies. Tazarotene (TZE), a third-generation retinoid and prodrug, is converted in the skin to its active form, tazarotenic acid (TZA). Its structure allows absorption of UVA/UVB light, prompting concerns about potential phototoxicity, but data on the excited state properties of TZE and… Read on PubMed →
Tower-shaped super-adhesive microneedles loaded with vitamin A-containing Bletilla striata vesicles: temporally regulated Inflammation resolution and ECM remodeling for scarless wound healing.
Journal of nanobiotechnology · 2026
Pathological scars, resulting from abnormal collagen metabolism during wound healing, pose clinical challenges due to the high recurrence rates of conventional treatments. Therefore, early-stage modulation of the wound healing process is emerging as a pivotal strategy for preventing and treating pathological scars, necessitating precise coordination of vascular regeneration, inflammation… Read on PubMed →
Clinical and Mechanistic Evidence for Comano Thermal Water: A Narrative Review.
International journal of molecular sciences · 2026
Comano thermal water (CTW) is a hypotonic, bicarbonate-calcium-magnesium mineral water traditionally used to manage chronic inflammatory and relapsing skin diseases. This review summarises and discusses the available clinical, experimental, and translational evidence on CTW, with a particular focus on dermatological indications. The physicochemical properties of CTW, along with the presence of a… Read on PubMed →
Efficacy of oral azithromycin versus oral doxycycline in treating moderate acne vulgaris and their effects on patients' quality of life.
Scientific reports · 2026
This study aimed to compare the efficacy of oral azithromycin with oral doxycycline in moderate acne vulgaris and to assess the corresponding changes in patient-reported quality-of-life. In this open label, randomised controlled trial conducted at a university student clinic, Muscat, Oman, 163 patients with moderate and severe acne vulgaris were assigned equally to receive either oral azithromycin… Read on PubMed →
Protective Effects of Astragalin Against Acute Ultraviolet B-Induced Photodamage in HaCaT Cells and Mouse Skin.
International journal of molecular sciences · 2026
Astragalin (AST), a natural flavonoid found in various plants, possesses antioxidant and anti-inflammatory properties. However, its protective efficacy against ultraviolet B (UVB)-induced cutaneous damage remains unclear. This study investigated the photoprotective effects of AST against UVB-induced photodamage using HaCaT keratinocytes and Kunming mice. In vitro, AST mitigated UVB-induced… Read on PubMed →
Comparison of Selected Pro-Health Biologically Active Chemical Compounds in Salviae herba from Selected Species.
Molecules (Basel, Switzerland) · 2026
Pharmaceutical, cosmetic, and food industries have contributed to the increasing interest in herbal phytochemicals. Salvia, a multifunctional culinary herb, meets phytotherapeutic requirements in the treatment of heartburn, excessive sweating, flatulence, and mouth, throat, and skin inflammatory conditions. Salviae folium is used in conductive education, i.e., a unique rehabilitation method for… Read on PubMed →
Psychosocial impact of acne among medical, Speech and Hearing Sciences, and Occupational Therapy undergraduates at a Sri Lankan University.
BMC psychology · 2026
BACKGROUND: Acne vulgaris is associated with substantial psychosocial effects, including impaired socioemotional well-being among young adults. This study aimed to determine the prevalence of acne and to examine the relationships and predictive effects of acne-related quality of life on psychological distress and self-esteem, in addition to exploring gender differences among medical and allied… Read on PubMed →
Pediculosis capitis: a hidden threat in tropical regions.
Clinical and experimental dermatology · 2026
Pediculosis capitis, caused by Pediculus humanus var. capitis, is a common ectoparasitic infestation primarily affecting school-aged children worldwide. It is transmitted through direct head-to-head contact and occasionally via fomites. Although it is not a vector for diseases, it causes significant psychosocial and economic burdens, including scalp itching, parental anxiety, absenteeism and… Read on PubMed →
Facile synthesis and synergistic cytotoxic effect of Ag/Co-ZnO nanoparticles in epithelial breast cancer cells.
Scientific reports · 2026
Here in, silver-cobalt (Ag/Co) incorporated in ZnO nanoparticles (NPs), referred to as Ag/Co-ZnO NPs, were synthesized using a facile co-precipitation method. The as-synthesized samples were characterized using ultraviolet-visible spectroscopy, field-emission scanning electron microscopy, Fourier transform infrared spectroscopy, and X-ray diffraction analysis techniques. The optical band gap of… Read on PubMed →
Novel Combination Of Antioxidants To Restore Healthy Intercellular Communication In An In vitro Model Using Conditioned Medium From Senescent Cells.
Journal of visualized experiments : JoVE · 2026
Skin aging is a multifactorial process driven by alterations at the molecular and cellular level, also known as hallmarks of aging. One of these alterations consists of altered intercellular communication, which contributes to skin tissue dysfunction and structural damage. Here, an in vitro model to mimic these skin aging features by incubating healthy fibroblasts with conditioned medium from… Read on PubMed →
Current materials and techniques in cosmetic hand injections.
Journal of plastic surgery and hand surgery · 2026
BACKGROUND: With the widespread popularity and development of aesthetic treatments, the focus has extended from facial aging to include the aging of hands. The primary aim of this study is to review the current materials, methods of injection, and testing procedures employed in cosmetic hand injections. METHODS: PubMed database (from 1971 to April 2024) was searched to identify relevant studies… Read on PubMed →
Innovative femoral vein valve repair combined with deep femoral vein ligation for treatment of chronic venous insufficiency: a case report.
Journal of cardiothoracic surgery · 2026
Chronic deep venous insufficiency (CVI) of the lower extremities results from structural or functional abnormalities of the venous valves, leading to blood reflux and increased venous pressure. Common clinical manifestations include edema, varicose veins, skin hyperpigmentation, and ulcers. The primary etiologies of CVI include congenital valve defects and secondary damage from venous thrombosis… Read on PubMed →