Research
Latest published research we're tracking.
The newest skincare and haircare papers from PubMed, linked to the ingredients we decode. Summaries are the authors' own abstracts — we excerpt, attribute, and link out to the source.
Showing research linked to Hyaluronic Acid (view profile)
Clear58 papers
Functional hyaluronic acid/gelatin hydrogel accelerates the closure and healing of diabetic wounds.
Carbohydrate polymers · 2026
The healing of extensive drug-resistant and skin area diabetic wounds poses significantly greater challenges compared to the recovery of typical wounds. Advanced approaches like tissue engineering and regenerative medicine hold promise, exemplified by hyaluronic acid/gelatin/poly(N-isopropyl acrylamide) (PNIPAm) hydrogel, a temperature-sensitive auto-shrinkage hydrogel with injectable biomimetic… Read on PubMed →
Enhanced corneal retention of hyaluronic acid via a metabolic glycoengineering-based in vivo bioorthogonal reaction.
Biomaterials science · 2026
Topical hyaluronic acid (HA) formulations have been extensively employed for managing various ocular diseases, but their therapeutic efficacy is severely compromised by rapid precorneal clearance due to a dense, negatively charged sialic acid-rich glycocalyx. To address this, we report a corneal surface engineering strategy that involves the metabolic incorporation of bioorthogonal azide groups… Read on PubMed →
ROS-Responsive Hydrogel Delivering Bio-Nanoselenium for Targeted Therapy of UVB-Induced Skin Photodamage.
ACS applied materials & interfaces · 2026
Ultraviolet B (UVB) radiation is a major environmental factor that induces skin photodamage through oxidative stress and inflammation. To address this, we developed a reactive oxygen species (ROS)-responsive hydrogel, SeNPs@HPTA, for the intelligent delivery of biogenic selenium nanoparticles (BioSeNPs) synthesized by Bifidobacterium animalis. The hydrogel was fabricated by cross-linking… Read on PubMed →
Current materials and techniques in cosmetic hand injections.
Journal of plastic surgery and hand surgery · 2026
BACKGROUND: With the widespread popularity and development of aesthetic treatments, the focus has extended from facial aging to include the aging of hands. The primary aim of this study is to review the current materials, methods of injection, and testing procedures employed in cosmetic hand injections. METHODS: PubMed database (from 1971 to April 2024) was searched to identify relevant studies… Read on PubMed →
Patient-specific 3D-printed scaffold for pediatric superior sternal cleft repair.
Journal of cardiothoracic surgery · 2026
RATIONALE: Sternal cleft is a rare congenital chest wall defect resulting from failed fusion of the sternal bars during embryogenesis. Primary closure is often feasible in the neonatal period due to thoracic wall compliance, but delayed presentations require complex reconstruction using autologous tissues, muscle flaps, and/or biomaterials. PATIENT CONCERNS: A two-year-old male presented with a… Read on PubMed →
Assessment of the efficiency of new regenerative gel and spray in experimental model systems.
BMC pharmacology & toxicology · 2026
INTRODUCTION: The problem of wound healing and the availability of effective and safe agents with regenerative properties is critically important today. The aim of the study was to develop an algorithm for evaluating products with regenerative potential using a set of in vitro and in vivo experimental models. METHODS: In vitro research included methods of working with cell culture. Studies were… Read on PubMed →
Dissolvable Microneedle Arrays Loaded with SCH772984 Targeting the MAPK/ERK Pathway to Inhibit Abnormal Vascular Proliferation in Hypertrophic Scars.
ACS biomaterials science & engineering · 2026
BACKGROUND: pathological angiogenesis is a critical driver of hypertrophic scar (HS) formation, a common fibrotic skin disorder with limited therapeutic options. However, the precise molecular pathways governing scar-associated neovascularization remain incompletely understood. This study aims to develop a biomaterial-based targeted delivery system to inhibit angiogenesis-driven HS… Read on PubMed →
Piceatannol from Passion Fruit Seed Waste: A Circular Bioeconomy-Driven Pathway Toward a Skin-Targeted Bioactive.
International journal of molecular sciences · 2026
Passiflora edulis (passion fruit) seed waste, an abundant by-product of the juice industry, is a promising source of piceatannol (PIC), a hydroxystilbene with superior antioxidant activity compared to resveratrol. However, its translation into a skin-targeted ingredient remains hindered by a lack of standardization and clinical validation. This review synthesizes current evidence on the… Read on PubMed →
Efficacy and safety of e.p.t.q. hyaluronic acid fillers in the context of aesthetic facial rejuvenation or beautification: a post-market clinical follow-up study.
Scientific reports · 2026
This study was conducted to assess the efficacy and safety of e.p.t.q. hyaluronic acid (HA) fillers (JETEMA Co., Ltd., Yongin, Korea) in the context of aesthetic facial rejuvenation or beautification. The patients were evaluated for changes in the Wrinkle Severity Rating Scale (WSRS) scores, the Mid-Face Volume Deficit Scale (MFVDS) scores and the Medicis Lip Fullness Scale (MLFS) scores at 24… Read on PubMed →
Comparative Efficacy and Patient-centered Outcomes of Intraoral Submucosal Zonal Injection Versus Traditional Extra-oral Injection for Improving Perioral Contour: A Randomized Controlled Trial.
Aesthetic plastic surgery · 2026
BACKGROUND: Intraoral injection techniques have been reported in various countries, with their advantages well documented. Drawing upon existing literature on intraoral injections, we developed a novel intraoral submucosal zonal injection technique that has demonstrated promising therapeutic outcomes. However, its efficacy and safety require further validation through standardized clinical… Read on PubMed →
Guide for Managing Vascular Occlusion Due to Fillers with Extended Neuro-Ophthalmic Involvement: A Review of Diagnosis, Classification and Treatment.
Aesthetic plastic surgery · 2026
INTRODUCTION: Filler-induced ophthalmic vascular occlusion (FIVO) is rare but devastating, while stroke remains even less frequent. Hyaluronic acid (HA) accounts for most reported cases of blindness. Given the emergency nature of these events, rapid recognition and immediate preparedness are paramount. METHODS: A systematic search of PubMed, Web of Science, and the Cochrane Library was conducted… Read on PubMed →
Optimization of Non-Cross-Linked Hyaluronic Acid and Adipose-Derived Mesenchymal Stem Cells for Regenerative Applications: an in Vitro Study.
Cell biochemistry and biophysics · 2026
Hyaluronic acid (HA) and adipose-derived mesenchymal stem cells (AD-MSCs) are both promising agents for skin rejuvenation. Combining non-cross-linked HA with AD-MSCs may enhance regenerative outcomes; however, the optimal HA concentration and its compatibility with AD-MSCs remain unclear. This study evaluated AD-MSCs encapsulated in varying concentrations of non-cross-linked HA, including a… Read on PubMed →
Role of HYAL1 on hyaluronan metabolism and the regulation of epidermal tight junction component CLDN1 in HaCaT cells.
Archives of biochemistry and biophysics · 2026
Hyaluronan (HA), a polysaccharide present in tissues throughout the body, exhibits various physiological functions depending on its molecular weight. Although high-molecular-weight HA (HM-HA) is produced in large amounts in the epidermal basal layer, low-molecular-weight HA (LM-HA) exists and acts as a moisturizing factor in the epidermal stratum corneum. However, the mechanism and physiological… Read on PubMed →
Albendazole-loaded chitosan nanoparticle conjugated with hyaluronic acid for the treatment of psoriasis.
Drug development and industrial pharmacy · 2026
OBJECTIVE: To design and develop hyaluronic acid (HA) conjugated Albendazole (ABZ) loaded chitosan nanoparticles (HA-ABZ-CSNP) loaded hydrogel for the treatment of psoriasis. SIGNIFICANCE: Albendazole (ABZ), a commonly used anti-parasitic drug, has garnered a lot of attention lately including anticancer and anti-psoriasis properties. Chitosan nanoparticle followed by conjugation with HA was… Read on PubMed →
pH-gated dual-modal switch photothermal cascade nanozyme hydrogel for diabetic infectious wound healing.
Biomaterials advances · 2026
Diabetic wounds are affected by hyperglycemia and neurovascular complications, and are often further exacerbated by bacterial infections, hypoxia, and insufficient collagen deposition. To overcome these pathological barriers, we have designed a pH-gated nanozyme cascade catalytic strategy for rapid bacterial eradication and skin regeneration. In this study, we first synthesized Prussian blue… Read on PubMed →
Minimally Invasive Aesthetic Treatments for the Corrective Patient Archetype: Transforming Lives.
Aesthetic plastic surgery · 2026
BACKGROUND: The definition of health encompasses mental, emotional, and social well-being, rather than simply the absence of disease. As a result, corrective aesthetic treatments are increasingly being viewed as an integral component of overall health rather than confined solely to the domain of aesthetics. In the realm of facial aesthetics, the corrective patient archetype is distinctly focused… Read on PubMed →
Engineering fast-acting anti-itching multifunctional dressing with quercetin-CD-MOF for atopic dermatitis.
Biomaterials advances · 2026
Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by susceptibility to infection and recurrent pruritus. Clinical treatment often focuses solely on skin lesions while neglecting direct control of pruritus symptoms. Herein, this study reports a novel powdered dressing (Que@CD@PH) that integrates in situ gelation, wet adhesion, and burst release of drugs for the treatment… Read on PubMed →
Preoperative Intravitreal Viscoelastic Injection (PIVOT) for Surgical Optimization in Rhegmatogenous Retinal Detachment With Choroidal Detachment.
Ophthalmic surgery, lasers & imaging retina · 2026
BACKGROUND AND OBJECTIVE: Rhegmatogenous retinal detachment with choroidal detachment (RRDCD) is a challenging situation. This study evaluates the safety and efficacy of preoperative intravitreal viscoelastic injection (PIVOT) in facilitating vitrectomy in RRD-CD. PATIENTS AND METHODS: This consecutive series included eight eyes of eight patients with RRD-CD (CD reaching to equator), managed… Read on PubMed →
Assessment of oxidative and inflammatory biomarkers in denture-related traumatic ulcers treated with different topical agents.
Archives of oral biology · 2026
OBJECTIVE: To investigate the potential role of oxidative and inflammatory status in saliva during the healing of denture-related traumatic ulcers, applying various topical agents. DESIGN: The prospective cohort study included 100 participants with denture-related traumatic ulcers, divided into five groups: traumatic ulcers that were not treated and treated with topical agents (0.2% hyaluronic… Read on PubMed →
Chitosan/hyaluronic acid-based hydrophobic-covalent double-network hydrogel: phenylalanine-mediated erythrocyte anchoring for rapid hemostasis, anti-swelling, and antioxidation.
International journal of biological macromolecules · 2026
This study addresses critical limitations of conventional hemostatic materials-such as significant swelling and inadequate adhesion to wet tissues-by developing an injectable and photocurable hydrogel (OPP-HAMA). The hydrogel is constructed through a rational molecular design: phenylalanine is grafted onto an oxidized chitosan backbone via a Schiff base reaction, thereby introducing hydrophobic… Read on PubMed →