Research
Latest published research we're tracking.
The newest skincare and haircare papers from PubMed, linked to the ingredients we decode. Summaries are the authors' own abstracts — we excerpt, attribute, and link out to the source.
Showing research linked to Chitosan (view profile)
Clear9 papers
Usnic Acid and Its Topical Use-A Concise Review.
Molecules (Basel, Switzerland) · 2026
Usnic acid (UA), a prominent lichen secondary metabolite, exhibits a unique dual therapeutic profile in dermatology, though its clinical translation is limited by systemic hepatotoxicity and poor solubility. This review comprehensively evaluates the topical efficacy, molecular mechanisms, and advanced formulation strategies of UA enantiomers and UA-rich extracts. A literature search across PubMed… Read on PubMed →
"Dual-Bottle, Dual-Mode" Intelligent Delivery System for Scenario-Specific Delivery of Astaxanthin and Skin Photoaging Protection.
ACS applied materials & interfaces · 2026
Astaxanthin (AX) faces several challenges in topical skin applications, including poor water solubility, low photostability, undesirable staining, and uncontrolled release. To address these, this study developed a "dual-bottle, dual-mode" intelligent delivery system. First, sulfobutylether-β-cyclodextrin (SBE-β-CD) inclusion technology was used to prepare an AX@SBE-β-CD inclusion complex, greatly… Read on PubMed →
Comparative Efficacy of Topical Chitosan and Minoxidil in Hair Loss: A Controlled Study With Microneedling.
The Journal of craniofacial surgery · 2026
BACKGROUND: Chitosan, a natural polysaccharide with immunomodulatory and regenerative properties, has shown promise in enhancing tissue repair. While 5% minoxidil remains the standard treatment for androgenetic alopecia, interest in non-hormonal or adjunctive therapies such as chitosan is growing. OBJECTIVE: To evaluate the clinical efficacy and safety of topical 2% chitosan applied after… Read on PubMed →
Albendazole-loaded chitosan nanoparticle conjugated with hyaluronic acid for the treatment of psoriasis.
Drug development and industrial pharmacy · 2026
OBJECTIVE: To design and develop hyaluronic acid (HA) conjugated Albendazole (ABZ) loaded chitosan nanoparticles (HA-ABZ-CSNP) loaded hydrogel for the treatment of psoriasis. SIGNIFICANCE: Albendazole (ABZ), a commonly used anti-parasitic drug, has garnered a lot of attention lately including anticancer and anti-psoriasis properties. Chitosan nanoparticle followed by conjugation with HA was… Read on PubMed →
pH-gated dual-modal switch photothermal cascade nanozyme hydrogel for diabetic infectious wound healing.
Biomaterials advances · 2026
Diabetic wounds are affected by hyperglycemia and neurovascular complications, and are often further exacerbated by bacterial infections, hypoxia, and insufficient collagen deposition. To overcome these pathological barriers, we have designed a pH-gated nanozyme cascade catalytic strategy for rapid bacterial eradication and skin regeneration. In this study, we first synthesized Prussian blue… Read on PubMed →
Chitosan/hyaluronic acid-based hydrophobic-covalent double-network hydrogel: phenylalanine-mediated erythrocyte anchoring for rapid hemostasis, anti-swelling, and antioxidation.
International journal of biological macromolecules · 2026
This study addresses critical limitations of conventional hemostatic materials-such as significant swelling and inadequate adhesion to wet tissues-by developing an injectable and photocurable hydrogel (OPP-HAMA). The hydrogel is constructed through a rational molecular design: phenylalanine is grafted onto an oxidized chitosan backbone via a Schiff base reaction, thereby introducing hydrophobic… Read on PubMed →
Multifunctional hydrogels loaded with tannic acid-modified MXene for synergistic photothermal/pharmacological treatment of infected wounds caused by drug-resistant bacteria.
Biomaterials advances · 2026
The development of advanced dressings capable of integrating multiple therapeutic modalities represents a promising strategy for promoting the healing of complex infected wounds. Herein, we developed a multifunctional hydrogel dressing (OC-MT-AG) based on tannic acid-modified MXene (MT) and ampicillin/ glutamine (AG) for the synergistic treatment of drug-resistant bacterial-infected wounds. The… Read on PubMed →
A multifunctional adhesive antibacterial chitosan/hyaluronic acid hydrogel enabling sustained release of human umbilical cord mesenchymal stem cell-derived exosomes for accelerated full-thickness skin repair.
International journal of biological macromolecules · 2026
Promoting skin wound healing is a major global public health challenge. Stem cell exosomes are regarded as a promising and ideal therapeutic approach. However, effective stem cell exosome therapy also depends on suitable vectors to promote the release and stability of exosomes. In this study, exosomes derived from human umbilical cord mesenchymal stem cells (UCMSCs-exo) were loaded into… Read on PubMed →
A review of biomacromolecular hydrogels inspired by regenerative organisms: Translating biological insights into tissue integration and regeneration.
International journal of biological macromolecules · 2026
Regenerative biology offers powerful insights into scarless healing and functional tissue integration, yet translating these biological principles into clinically effective biomaterials remains a major challenge. Biological macromolecule-based hydrogels, derived from natural proteins and polysaccharides, have emerged as promising platforms to bridge this gap due to their intrinsic bioactivity… Read on PubMed →