Research
Latest published research we're tracking.
The newest skincare and haircare papers from PubMed, linked to the ingredients we decode. Summaries are the authors' own abstracts — we excerpt, attribute, and link out to the source.
Showing research linked to Benzisothiazolinone (view profile)
Clear4 papers
Isothiazolinones in Disposable Rubber Gloves-Results of Chemical Analysis.
Contact dermatitis · 2026
BACKGROUND: Contact allergy to benzisothiazolinone (BIT) has increased in recent years, but exposure to it is not always found. It's important to know whether the gloves might be an isothiazolinone source especially in patients with symptoms from gloves and isothiazolinone contact allergy with or without allergy to rubber chemicals. OBJECTIVES: To present results of chemical analysis of… Read on PubMed →
Prevalence of Contact Allergy to Isothiazolinones in Dermatitis Patients From 2000 to 2025: A Systematic Review and Meta-Analysis.
Contact dermatitis · 2026
Isothiazolinones are employed in the preservation of cosmetic, consumer and industrial products, with the objective of preventing deterioration and spoilage. However, the utilization of isothiazolinones is associated with an elevated risk of developing contact allergy (CA). Herein, we assess the epidemiology of CA to isothiazolinones among dermatitis patients from year 2000 onwards. We… Read on PubMed →
Development of a Generic Analysis Method for Isothiazolinones in Consumer Products Prompted by Increased Sensitisation to Benzisothiazolinone.
Contact dermatitis · 2026
BACKGROUND: Isothiazolinones are widely used as preservatives in both cosmetic and non-cosmetic products. Sensitisation to isothiazolinones other than chloromethylisothiazolinone/methylisothiazolinone (CMIT/MIT), present in the baseline series, is increasing. OBJECTIVES: To investigate the prevalence of sensitisation to benzisothiazolinone (BIT) in comparison to CMIT/MIT and to develop a… Read on PubMed →
Trends in Contact Allergy to Preservatives From 2014 to 2023: Benzisothiazolinone on the Rise.
Contact dermatitis · 2025
<h4>Background</h4>Skin sensitising preservatives are commonly used in consumer and industrial products. The widespread use of preservatives has led to recurrent epidemics of contact allergy.<h4>Objectives</h4>To investigate temporal trends of contact allergy to preservatives from 2014 to 2023.<h4>Materials and methods</h4>Patients consecutively patch tested with preservatives from the European… Read on PubMed →