Research
Latest published research we're tracking.
The newest skincare and haircare papers from PubMed, linked to the ingredients we decode. Summaries are the authors' own abstracts — we excerpt, attribute, and link out to the source.
Showing research linked to Tyrosinase (view profile)
Clear5 papers
Food-derived components as natural skin-whitening strategies: Classification, mechanisms, application forms and prospects.
Food research international (Ottawa, Ont.) · 2026
BACKGROUND: Skin hyperpigmentation has attracted widespread attention. Traditional chemical skin-whitening components pose potential risks, whereas food-derived skin-whitening components are gaining increasing attention owing to their natural food sources and high biocompatibility. SCOPE AND METHODS: This review was conducted by comprehensively searching Google Scholar, Wiley, and Taylor &… Read on PubMed →
Structure-Based Virtual Screening and Mechanistic Characterization of Methotrexate and Selinexor as Potent Anti-Melanogenic Agents via Multi-Pathway Suppression of MITF.
Cells · 2026
Tyrosinase is a pivotal therapeutic target for hyperpigmentation disorders, yet current inhibitors frequently exhibit limited potency and suboptimal safety. Here, we employed structure-based virtual screening of an FDA-approved drug library against a refined human tyrosinase homology model, identifying methotrexate and selinexor as potent anti-melanogenic candidates. Both compounds markedly… Read on PubMed →
Anti-Photoaging and Anti-Melanogenic Effects of a Novel Lactiplantibacillus plantarum RKBP Isolated from Giant Centella asiatica.
Journal of microbiology and biotechnology · 2026
Ultraviolet B (UVB) irradiation is a major contributor to photoaging and hyperpigmentation, leading to collagen damage and excessive melanin accumulation. This study investigated the anti-photoaging and anti-melanogenic effects of heat-killed L. plantarum RKBP isolated from Giant Centella asiatica. L. plantarum RKBP was prepared by thermal inactivation and evaluated for anti-photoaging effects… Read on PubMed →
Ethanolic Extract of Padina arborescens Suppresses Melanogenesis and Attenuates UVB-Induced Photodamage in Cellular and Zebrafish Models.
International journal of molecular sciences · 2026
Ultraviolet (UV) irradiation induces complex skin damage, including hyperpigmentation, oxidative stress, and alterations in proteins related to keratinocyte differentiation and epidermal barrier-associated status. This study investigated the multifunctional protective effects of Padina arborescens ethanolic extract (PAEE) against skin damage in melanocytes, keratinocytes, and zebrafish. In… Read on PubMed →
Bioactive levan polysaccharides in cosmeceutical applications: A review.
International journal of biological macromolecules · 2026
Levan, a β-(2,6)-linked fructose homopolysaccharide, has gained increasing attention as a multifunctional biopolymer for cosmetic and cosmeceutical applications. Owing to its distinctive molecular architecture, levan uniquely combines high molecular weight, pronounced bioadhesive capacity, and remarkably low intrinsic viscosity, which facilitates its integration into diverse formulation platforms… Read on PubMed →