Research
Latest published research we're tracking.
The newest skincare and haircare papers from PubMed, linked to the ingredients we decode. Summaries are the authors' own abstracts — we excerpt, attribute, and link out to the source.
Showing research linked to Spironolactone (view profile)
Clear6 papers
Hormonal acne therapies in pediatrics.
Current opinion in pediatrics · 2026
BACKGROUND: Acne vulgaris is one of the most common inflammatory skin conditions in adolescents, affecting up to 85% of individuals aged 12-24 years. Beyond its physical manifestations, acne can significantly impact self-esteem, quality of life, and psychological well-being. DISCUSSION: Acne has a multifactorial pathogenesis involving follicular hyperkeratinization, increased sebum production… Read on PubMed →
Safety and tolerability of combination oral spironolactone and low-dose oral minoxidil for hair loss in adult females: A retrospective cohort study.
Journal of the American Academy of Dermatology · 2026
BACKGROUND: Spironolactone and oral minoxidil are effective female alopecia monotherapies. Combination therapy is commonly used, though safety and tolerability data are limited. OBJECTIVE: To assess safety and tolerability by adverse effect incidence. METHODS: Retrospective cohort study conducted in females aged ≥18 taking combination therapy for hair loss. RESULTS: A total of 432 patients were… Read on PubMed →
Prescribing Habits for Androgenetic Alopecia Among Dermatologists in Spain in 2024: A Cross-Sectional Study.
Actas dermo-sifiliograficas · 2026
The management of androgenetic alopecia (AGA) is evolving. This study updates current prescribing practices compared with 2019-2020. A digital survey was conducted among dermatologists in Spain between March and June 2024, focusing on AGA treatment trends, nutricosmetic product selection, and the adoption of hair skinification. A total of 202 dermatologists participated, including 164 attending… Read on PubMed →
Racial Differences in Dermatologic Treatment for Adolescents With PCOS-Related Acne Vulgaris.
Pediatric dermatology · 2026
BACKGROUND/OBJECTIVES: Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women, with acne frequently appearing during adolescence. Racial and ethnic disparities in PCOS phenotype and adult acne treatment are well documented, yet differences in acne management among adolescents with PCOS remain unclear. This study evaluated racial and ethnic differences in acne treatment patterns… Read on PubMed →
Update of the EuroGuiDerm evidence-based guideline for the treatment of acne-Short version.
Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
This evidence- and consensus-based guideline for the treatment of acne was developed in accordance with the EuroGuiDerm Guideline and Consensus Statement Development Manual. This guideline is an update of the 2016 version. This is a short summary of the full version of the EuroGuiDerm Evidence-based Guideline for the Treatment of Acne. For the complete guideline text, detailed methods report, and… Read on PubMed →
New Agents for Acne Treatment and Updates to Isotretinoin Guidelines.
Pediatric clinics of North America · 2026
Acne is an inflammatory condition that can affect quality of life. New topical treatments include tazarotene lotion, trifarotene, combined microencapsulated benzoyl peroxide and tretinoin, minocycline foam, topical dapsone, and clascoterone cream. More recent systemic options include subantimicrobial doxycycline, sarecycline, combined oral contraceptives, spironolactone, and isotretinoin-lidose. Read on PubMed →