Research
Latest published research we're tracking.
The newest skincare and haircare papers from PubMed, linked to the ingredients we decode. Summaries are the authors' own abstracts — we excerpt, attribute, and link out to the source.
Showing research linked to Skin Lipids (view profile)
Clear4 papers
Absorption and Effects of Patch Test Preparations of Hydroperoxides of Limonene and Hydroperoxides of Linalool in Human Ex Vivo Skin.
Contact dermatitis · 2026
BACKGROUND: Limonene and linalool are fragrance terpenes that undergo autoxidation to sensitizing hydroperoxides. This study assessed the penetration of limonene hydroperoxide and linalool hydroperoxide from patch test preparations in ex vivo human skin samples, alongside analysing the effects of the patch test preparations on the composition of skin lipids, using Time-of-Flight Secondary Ion Mass… Read on PubMed →
Biallelic GLTP mutations cause nonsyndromic epidermal differentiation disorder via disrupted epidermal glucosylceramide transport.
The Journal of clinical investigation · 2026
Ceramides are essential skin lipids for maintaining the mammalian skin permeability barrier, which protects against external stimuli. The precursor of epidermal ceramides, glucosylceramides (GlcCer), is synthesized within granular keratinocytes while its precise cellular transport mechanisms remain poorly characterized. Here, we identified 3 pathogenic variants in the GLTP gene, which encodes… Read on PubMed →
Skin Lipids and Their Influence on Skin Microbiome and Skin Care.
ACS omega · 2025
Skin lipids are essential components that play crucial roles in maintaining the skin barrier, preventing transepidermal water loss, and protecting against external agents. The specific composition of lipids may vary according to factors, such as age, diet, and environmental conditions. They are found predominantly in the stratum corneum, the outermost layer of the epidermis, with lipids… Read on PubMed →
Mass Spectrometry Imaging Elucidates the Precise Localization and Site-Specific Functions of Skin Lipids.
International journal of molecular sciences · 2025
Lipids are essential for the skin, playing a crucial role in forming plasma membranes and maintaining the skin's permeability barrier and hydration. Intercellular lipids fill the spaces between corneocytes and contribute to the barrier function. Lipid abnormalities in the skin have been observed in many skin diseases, including atopic dermatitis and psoriasis. However, the specific localization… Read on PubMed →