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Research

Latest published research we're tracking

The newest skincare and haircare papers from PubMed, linked to the ingredients we decode. Summaries are the authors' own abstracts — we excerpt, attribute, and link out to the source.

Showing research linked to Polyethylene (view profile)

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7 papers

Vitamin C

Dual-mechanism vitamin C delivery by polyethylene glycol-23 glyceryl distearate-based niosomes via SVCT2 induction and enhanced transdermal penetration.

Drug delivery · 2026

Polyethylene glycol-23 glyceryl distearate (GDS-23)-a noisome-forming diacylglycerol-polyethylene glycol-based nonionic surfactant-functions as a nanocarrier for drug delivery systems (DDS) and an enhancer of endogenous antioxidant capacity through nuclear factor erythroid 2-related factor 2 (Nrf2) activation. Here, we evaluated the potential of GDS-23 as a multifunctional DDS carrier by… Read on PubMed →

Vitamin C

A flexible multichannel wearable sensor for real-time monitoring of exercise-induced sweat composition.

Talanta · 2026

To address low sensitivity, severe environmental interference, single-analyte detection, and traditional rigid substrates' inability to adapt to dynamic skin deformation in surface metabolite detection, polyethylene terephthalate (PET) was selected as the flexible substrate. A multi-channel flexible wearable biosensor with mechanical adaptability and multi-parameter detection capability was… Read on PubMed →

Hyaluronic acid

Chitosan/hyaluronic acid-based hydrophobic-covalent double-network hydrogel: phenylalanine-mediated erythrocyte anchoring for rapid hemostasis, anti-swelling, and antioxidation.

International journal of biological macromolecules · 2026

This study addresses critical limitations of conventional hemostatic materials-such as significant swelling and inadequate adhesion to wet tissues-by developing an injectable and photocurable hydrogel (OPP-HAMA). The hydrogel is constructed through a rational molecular design: phenylalanine is grafted onto an oxidized chitosan backbone via a Schiff base reaction, thereby introducing hydrophobic… Read on PubMed →

Hyaluronic acid

Cross-Linked Sodium Hyaluronate Filler Containing Poly-L-Lactic Acid-b-Poly (Ethylene Glycol) Microspheres for Periorbital Rejuvenation: A Multimodal Assessment of Physicochemical, Preclinical, and Clinical Performance.

Journal of cosmetic dermatology · 2026

BACKGROUND: Periorbital rejuvenation presents significant challenges: hyaluronic acid (HA) fillers carry risks of edema and the Tyndall effect, whereas traditional poly-L-lactic acid (PLLA) may lead to nodule formation and delayed inflammatory reactions. To address these limitations, the PLLA-b-poly (ethylene glycol) (PLLA-b-PEG)/HA composite filler is designed to optimize tissue compatibility and… Read on PubMed →

Melasma & dark spots

Interferon Alpha-2a as Treatment for Primary Acquired Melanosis With Atypia and for Primary Acquired Melanosis With Atypia Surrounding Conjunctival Melanoma.

American journal of ophthalmology · 2026

PURPOSE: To report on topical treatment with interferon (IFN) alfa-2a for conjunctival primary acquired melanosis (PAM) with atypia. DESIGN: A retrospective interventional case series. SUBJECTS: Patients diagnosed with PAM with atypia. METHODS: Patients received topical IFN α-2a, IFN α-2b, or pegylated IFN α-2a. Treatment duration, response, adverse effects, and progression-free survival (PFS)… Read on PubMed →

Melasma & dark spots

A randomized controlled trial of 3% polidocanol foam with saline prewashing compared with standard foam sclerotherapy for the treatment of varicose veins.

Journal of vascular surgery. Venous and lymphatic disorders · 2026

BACKGROUND: Chronic venous disease is a highly prevalent global condition. Sclerotherapy with polidocanol foam is an established minimally invasive treatment. However, complications such as postprocedural hyperpigmentation remain common, and the maximum injectable volume per session may limit treatment efficacy. These factors highlight the need for optimized techniques to enhance vein occlusion… Read on PubMed →

Azelaic acid

Topical PEGylated azelaic acid nanohybrids: A lipid-polymer hydrogel system for sustained dermal delivery in rosacea management.

Colloids and surfaces. B, Biointerfaces · 2026

Rosacea is a chronic inflammatory disorder of the central face characterized by persistent erythema, flushing, and inflammatory papules. Azelaic acid (Az) is a first-line topical therapy for papulopustular rosacea; however, its clinical efficacy is limited by poor aqueous solubility and restricted penetration across the stratum corneum. To overcome these limitations, PEGylated lipid-polymer hybrid… Read on PubMed →

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