Research
Latest published research we're tracking.
The newest skincare and haircare papers from PubMed, linked to the ingredients we decode. Summaries are the authors' own abstracts — we excerpt, attribute, and link out to the source.
Showing research linked to Hyaluronidase (view profile)
Clear4 papers
Guide for Managing Vascular Occlusion Due to Fillers with Extended Neuro-Ophthalmic Involvement: A Review of Diagnosis, Classification and Treatment.
Aesthetic plastic surgery · 2026
INTRODUCTION: Filler-induced ophthalmic vascular occlusion (FIVO) is rare but devastating, while stroke remains even less frequent. Hyaluronic acid (HA) accounts for most reported cases of blindness. Given the emergency nature of these events, rapid recognition and immediate preparedness are paramount. METHODS: A systematic search of PubMed, Web of Science, and the Cochrane Library was conducted… Read on PubMed →
Role of HYAL1 on hyaluronan metabolism and the regulation of epidermal tight junction component CLDN1 in HaCaT cells.
Archives of biochemistry and biophysics · 2026
Hyaluronan (HA), a polysaccharide present in tissues throughout the body, exhibits various physiological functions depending on its molecular weight. Although high-molecular-weight HA (HM-HA) is produced in large amounts in the epidermal basal layer, low-molecular-weight HA (LM-HA) exists and acts as a moisturizing factor in the epidermal stratum corneum. However, the mechanism and physiological… Read on PubMed →
Hyaluronic Acid Dermal Filler-Associated Vascular Occlusion-A Review of Prevention and Management Strategies.
Journal of cosmetic dermatology · 2026
BACKGROUND: Significant complications are uncommon with aesthetic hyaluronic acid (HA) dermal fillers, but inadvertent injection of dermal filler into an artery can result in tissue damage, scarring, visual loss, and even stroke. Practitioners must therefore reduce this risk through proactive, preventative techniques. Early recognition of vascular occlusion (VO) is also crucial to minimize… Read on PubMed →
Hyaluronidase Reverses the Effect of Hyaluronic Acid Without Destroying Normal Skin Structure.
Journal of cosmetic dermatology · 2026
BACKGROUND: Dermal fillings based on hyaluronic acid have been widely used in facial rejuvenation. A number of studies have reported the beneficial effect of hyaluronidase in saving the complications of hyaluronic acid. However, the effects of hyaluronidase on dermal matrix, skin structure, and fibroblast function are unknown. METHOD: In this study, hyaluronic acid and hyaluronidase were injected… Read on PubMed →