Research

Latest published research we're tracking

The newest skincare and haircare papers from PubMed, linked to the ingredients we decode. Summaries are the authors' own abstracts — we excerpt, attribute, and link out to the source.

Showing research linked to Tyrosinase (view profile)

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3 papers under Melasma & dark spots

Melasma & dark spots

Food-derived components as natural skin-whitening strategies: Classification, mechanisms, application forms and prospects.

Food research international (Ottawa, Ont.) · 2026

BACKGROUND: Skin hyperpigmentation has attracted widespread attention. Traditional chemical skin-whitening components pose potential risks, whereas food-derived skin-whitening components are gaining increasing attention owing to their natural food sources and high biocompatibility. SCOPE AND METHODS: This review was conducted by comprehensively searching Google Scholar, Wiley, and Taylor &… Read on PubMed →

Melanin Tyrosinase

DOI

Melasma & dark spots

Structure-Based Virtual Screening and Mechanistic Characterization of Methotrexate and Selinexor as Potent Anti-Melanogenic Agents via Multi-Pathway Suppression of MITF.

Cells · 2026

Tyrosinase is a pivotal therapeutic target for hyperpigmentation disorders, yet current inhibitors frequently exhibit limited potency and suboptimal safety. Here, we employed structure-based virtual screening of an FDA-approved drug library against a refined human tyrosinase homology model, identifying methotrexate and selinexor as potent anti-melanogenic candidates. Both compounds markedly… Read on PubMed →

Melanin Methotrexate Tyrosinase

DOI

Melasma & dark spots

Anti-Photoaging and Anti-Melanogenic Effects of a Novel Lactiplantibacillus plantarum RKBP Isolated from Giant Centella asiatica.

Journal of microbiology and biotechnology · 2026

Ultraviolet B (UVB) irradiation is a major contributor to photoaging and hyperpigmentation, leading to collagen damage and excessive melanin accumulation. This study investigated the anti-photoaging and anti-melanogenic effects of heat-killed L. plantarum RKBP isolated from Giant Centella asiatica. L. plantarum RKBP was prepared by thermal inactivation and evaluated for anti-photoaging effects… Read on PubMed →

Melanin Tyrosinase

DOI

Food-derived components as natural skin-whitening strategies: Classification, mechanisms, application forms and prospects.

Structure-Based Virtual Screening and Mechanistic Characterization of Methotrexate and Selinexor as Potent Anti-Melanogenic Agents via Multi-Pathway Suppression of MITF.

Anti-Photoaging and Anti-Melanogenic Effects of a Novel Lactiplantibacillus plantarum RKBP Isolated from Giant Centella asiatica.

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