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Assessing the skin sensitization potential of fragrance ingredients in consumer products using the peroxidase peptide reactivity assay (PPRA) as an additional weight of evidence.

Toxicology in vitro : an international journal published in association with BIBRA · 2026

A fragrance ingredient's potential to induce skin sensitization is an important factor in risk assessment. The key events in the skin sensitization adverse outcome pathway (AOP) can be evaluated with new approach methodologies (NAMs) for hazard identification, potency, and point of departure (PoD) derivation, distinguishing between sensitizers and non-sensitizers. The first key event is the… Read on PubMed →