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Ingredient pairing

Can I use niacinamide with retinol?

Short answerYesModerate evidence: At least one human study or a well-supported mechanism, but not yet full scientific consensus.

Yes — a cited synergy. Niacinamide raises stratum-corneum ceramide/fatty-acid synthesis, repairing the barrier retinoids disrupt, so it eases erythema and peeling while retinoid efficacy is maintained.

Read the full profile: niacinamide →

Sources

  1. 1.Tanno O et al. Nicotinamide increases biosynthesis of ceramides and improves the epidermal permeability barrier. Br J Dermatol 2000 ↗
  2. 2.Niacinamide/peptide/retinyl-propionate regimen vs 0.02% tretinoin for wrinkles: RCT. PMC ↗

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