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Arachidonic Acid
In cosmetic formulas, Arachidonic Acid softens and smooths the skin, and also leaves skin feeling smoother or better cared for.
What does Arachidonic Acid do in a formula?
Arachidonic Acid softens and smooths the skin, and also leaves skin feeling smoother or better cared for.
The listed functions explain its role in a formula. They do not establish whether a finished product will suit your skin.
No reviewed benefit claim is available here yet. Compare the complete formula, its directions, and your own skin preferences.
What a CosIng listing meansCurrently found on
Beauty reading & sources
Research papers (19)
Related papers naming this ingredient in their title or in a beauty-relevant abstract passage. Laboratory, clinical and exposure studies have different scopes; these links are not reviewed benefit claims.
- Exploring clinical and genetic evidence in association between unsaturated fatty acids and acne.
European journal of nutrition · 2025
- Impact of EPA ingestion on COX- and LOX-mediated eicosanoid synthesis in skin with and without a pro-inflammatory UVR challenge--report of a randomised controlled study in humans.
Molecular nutrition & food research · 2014
Oral or dietary context; not evidence for topical use.
- Highly selective phosphodiesterase 4 inhibitors for the treatment of allergic skin diseases and psoriasis.
Inflammation & allergy drug targets · 2007
See 16 more research papers
- Exploring the Toxicological Impact of Bisphenol A on Acne Vulgaris via the PLA2G2A-Arachidonic Acid Pathway.
Clinical, cosmetic and investigational dermatology · 2026
- Comparative Efficacy of Skin-Lightening Formulations in Suppressing Ultraviolet B (UVB)-Induced Arachidonic Acid, Alpha-Melanocyte-Stimulating Hormone (α-MSH), and Melanin Expression: An In Vitro Keratinocyte-Melanocyte Co-culture Study.
Cureus · 2025
- Deciphering the Skin Anti-Aging and Hair Growth Promoting Mechanisms of Opophytum forskahlii Seed Oil via Network Pharmacology.
International journal of molecular sciences · 2025
- New insights into the role of Cutibacterium acnes-derived extracellular vesicles in inflammatory skin disorders.
Scientific reports · 2023
- Exogenous Arachidonic Acid Affects Fucoxanthin Biosynthesis and Photoprotection in Phaeodactylum tricornutum.
Marine drugs · 2022
- Prostaglandin E2 Induces Skin Aging via E-Prostanoid 1 in Normal Human Dermal Fibroblasts.
International journal of molecular sciences · 2019
- Decreased eicosapentaenoic acid levels in acne vulgaris reveals the presence of a proinflammatory state.
Prostaglandins & other lipid mediators · 2017
- Differential effectiveness of selected non-psychotropic phytocannabinoids on human sebocyte functions implicates their introduction in dry/seborrhoeic skin and acne treatment.
Experimental dermatology · 2016
- Role of Arachidonic Acid in Promoting Hair Growth.
Annals of dermatology · 2016
- Deficiency of n-6 polyunsaturated fatty acids is mainly responsible for atopic dermatitis-like pruritic skin inflammation in special diet-fed hairless mice.
Experimental dermatology · 2013
- Assessment of skin absorption and irritation potential of arachidonic acid and glyceryl arachidonate using in vitro diffusion cell techniques.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2007
- Essential-fatty-acid metabolites in plasma phospholipids in patients with ichthyosis vulgaris, acne vulgaris and psoriasis.
Clinical and experimental dermatology · 1990
- Suppression of the cutaneous immune response following topical application of the prostaglandin PGE2.
Cellular immunology · 1987
- Levels of arachidonic acid and its metabolites in the skin in human allergic and irritant contact dermatitis.
The British journal of dermatology · 1984
- Production of intraepidermal microabscesses by topical application of leukotriene B4.
The Journal of investigative dermatology · 1984
- Arachidonic acid metabolism in skin: experimental contact dermatitis in guinea pigs.
International archives of allergy and applied immunology · 1982
PubMed is hosted by the U.S. National Library of Medicine. Listing there does not mean NIH authored or endorses a paper.
Cosmetic ingredient references
- Arachidonic Acid in COSMILE Europe
Industry ingredient directory · matched to the publisher’s ingredient index.
- European Commission CosIng database
Catalog reference 74354. Database inclusion is not approval or proof of safety or effectiveness.
Which papers mention Arachidonic Acid?
The research feed contains 6 linked papers (2025-2026).
Highlights below name the ingredient or a recorded alias in their titles. A mention does not establish a skincare benefit: a paper may study oral use, a combination formula, or a different population. Reviewed ingredient claims, when available, are assessed separately for their stated scope.
No title-matched highlights are available here. Browse the full linked feed for additional papers.
Where it fits in real formulas
Related ingredients, common formula neighbors, naming, and catalog context. This stays separate from evidence and personal-fit guidance.
Similar ingredients
related by documented function or concern
SqualaneSoftens and smooths skinArgan oilSoftens and conditions skin as an emollientBakuchiolA 12-week head-to-head study found similar improvement in measured wrinkles with bakuchiol and retinolHyaluronic Acid (salt form)Pulls water into the skin for immediate hydration and a plumper lookPro-vitamin B5Moisturizes and improves hydration by drawing and holding water in the skinAllantoinHelps condition and soften the skin surface
Which products contain Arachidonic Acid?
All 2 →2 public products list this ingredient.
Catalog preview
A compact look at the first products in this result set
1–1 / 2
About the sources
Ingredient lists show presence and order, not concentration, pH, ingredient grade, delivery system, or finished-formula performance.
Sources & methodologyCompiled from the EU CosIng database (ref 74354) · snapshot 16 June 2026. CosIng is an informational, non-legally-binding reference. Inclusion does not mean an ingredient is approved, safe, authorized for cosmetic use, or clinically effective. An INCI list does not reveal concentration, pH, ingredient grade, delivery system, or finished-formula performance.