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Latest published research we're tracking

The newest skincare and haircare papers from PubMed, linked to the ingredients we decode. Summaries are the authors' own abstracts — we excerpt, attribute, and link out to the source.

Showing research linked to Tranexamic Acid (view profile)

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3 papers under Melasma & dark spots

Melasma & dark spots

The efficacy of tranexamic acid in prevention and treatment of post-inflammatory hyperpigmentation: a pilot study.

Clinical and experimental dermatology · 2026

Post-inflammatory hyperpigmentation (PIH) is a common complication following trauma or cutaneous inflammation, particularly affecting individuals with skin of colour. Tranexamic acid (TXA) is a lysine analogue with antifibrinolytic properties and has been used as an off-label agent for melasma and procedural PIH. This pilot study evaluated the efficacy of oral TXA in the prevention and treatment… Read on PubMed →

Tranexamic AcidLysine
DOI
Melasma & dark spots

Tranexamic acid protects human dermal fibroblasts from D-galactose-induced senescence via the GPR30/MAPK pathway.

Annals of medicine · 2026

BACKGROUND: Tranexamic acid (TXA) is widely used for pigmentary disorders, but its anti-ageing potential remains unclear. This study aimed to evaluate whether topical 3% TXA improves early periorbital wrinkles in women with facial melasma and to investigate whether TXA protects human dermal fibroblasts from D-galactose-induced senescence via the GPR30/MAPK pathway. METHODS: Fifty women with… Read on PubMed →

Tranexamic AcidGalactoseOxygen
DOI
Melasma & dark spots

Exploring the mechanism of differential responses to combination therapy in melasma: pigmentary versus mixed pigmentary-vascular types-a clinical study based on interaction analysis.

The Journal of dermatological treatment · 2026

BACKGROUND: Melasma shows clinical heterogeneity, but the role of vascular components in treatment resistance remains unclear. METHODS: This retrospective cohort study included 75 melasma patients stratified by severity (mild/moderate/severe, n = 25 each) and classified into pure pigmentary (M-type, n = 42) and mixed pigmentary-vascular (M + V-type, n = 33). All received low-fluence Q-switched… Read on PubMed →

Tranexamic Acid
DOI

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