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Fibroblast-directed melanocyte recruitment via Cxcl12-Cxcr4 axis promotes post-inflammatory hyperpigmentation and skin barrier protection in zebrafish.

Journal of genetics and genomics = Yi chuan xue bao · 2026

Post-inflammatory hyperpigmentation (PIH) is a common skin disorder characterized by brown or black macules. It can be categorized as transient, typically resolving within 6-12 months, or permanent, persisting for years. While the pathogenesis of PIH is commonly linked to localized melanocyte overactivation, the precise cellular and molecular basis for this dysregulation, as well as its… Read on PubMed →