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Ingredient

Zinc Pyrithione

The classic anti-dandruff active, a zinc compound with antifungal and antibacterial action.

Key facts

INCI name
Zinc Pyrithione
Evidence grade
moderate evidence
Reviewed

Similar ingredients

others that do something alike

What it does

moderate evidence

It works mainly by targeting the Malassezia yeast behind dandruff and seborrheic dermatitis, flooding the fungal cells with zinc and shutting down their energy production to calm flaking, itch, and scaling.

Benefits

  • Effective, time-tested treatment for dandruff and seborrheic dermatitis
  • Antifungal and antibacterial, targeting the Malassezia yeast that drives flaking
  • Reduces scalp itch, redness, and scaling
  • Well established in over-the-counter shampoos and washes

Side effects

  • Can occasionally cause mild irritation, dryness, or itching
  • Rarely, allergic skin reactions in sensitive individuals

Who it's for

Dandruff, flaky scalp, and seborrheic dermatitis

Who should be careful

Banned from cosmetics in the EU since 2021 over reproductive-toxicity concerns (still OTC-approved in the US); pregnant or breastfeeding users may prefer an alternative anti-dandruff active

Products with Zinc Pyrithione (7)

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